Literature DB >> 27582644

Advances in Biomarkers: Going Beyond the Carcinoembryonic Antigen.

Nicole E Lopez1, Carrie Y Peterson2.   

Abstract

Using biologically available markers to guide treatment decisions in colorectal cancer care is becoming increasingly common, though our understanding of these biomarkers is in its infancy. In this article, we will discuss how this area is rapidly changing, review important biomarkers being used currently, and explain how the results influence clinical decision-making. We will also briefly discuss the possibility of a liquid biopsy and explore several exciting and new options.

Entities:  

Keywords:  Lynch syndrome; carcinoembryonic antigen; hereditary colon cancer; polyposis

Year:  2016        PMID： 27582644      PMCID： PMC4988861          DOI： 10.1055/s-0036-1584289

Source DB:  PubMed          Journal:  Clin Colon Rectal Surg        ISSN： 1530-9681


  95 in total

1.  Genetic dissimilarity between primary colorectal carcinomas and their lymph node metastases: ploidy, p53, bcl-2, and c-myc expression--a pilot study.

Authors:  Khaled Refaat Zalata; Mohamed Farouk Elshal; Abd AlRahman Mohammad Foda; Ashraf Shoma
Journal:  Tumour Biol       Date:  2015-04-04

Review 2.  Molecular profiling of colon tumors: the search for clinically relevant biomarkers of progression, prognosis, therapeutics, and predisposition.

Authors:  Manny D Bacolod; Francis Barany
Journal:  Ann Surg Oncol       Date:  2011-02-24       Impact factor: 5.344

Review 3.  Extended RAS mutations and anti-EGFR monoclonal antibody survival benefit in metastatic colorectal cancer: a meta-analysis of randomized, controlled trials.

Authors:  M J Sorich; M D Wiese; A Rowland; G Kichenadasse; R A McKinnon; C S Karapetis
Journal:  Ann Oncol       Date:  2014-08-12       Impact factor: 32.976

4.  Five-year follow-up after radical surgery for colorectal cancer. Results of a prospective randomized trial.

Authors:  J T Mäkelä; S O Laitinen; M I Kairaluoma
Journal:  Arch Surg       Date:  1995-10

Review 5.  Molecular detection of circulating cancer cells. Role in diagnosis, prognosis and follow-up of colon cancer patients.

Authors:  Bela Molnar; Ferenc Sipos; Orsolya Galamb; Zsolt Tulassay
Journal:  Dig Dis       Date:  2003       Impact factor: 2.404

6.  Frequency and parental origin of de novo APC mutations in familial adenomatous polyposis.

Authors:  Stefan Aretz; Siegfried Uhlhaas; Reiner Caspari; Elisabeth Mangold; Constanze Pagenstecher; Peter Propping; Waltraut Friedl
Journal:  Eur J Hum Genet       Date:  2004-01       Impact factor: 4.246

7.  Microsatellite instability has a positive prognostic impact on stage II colorectal cancer after complete resection: results from a large, consecutive Norwegian series.

Authors:  M A Merok; T Ahlquist; E C Røyrvik; K F Tufteland; M Hektoen; O H Sjo; T Mala; A Svindland; R A Lothe; A Nesbakken
Journal:  Ann Oncol       Date:  2012-12-12       Impact factor: 32.976

8.  The expression of microRNA-375 in plasma and tissue is matched in human colorectal cancer.

Authors:  Lingling Xu; Minzhe Li; Min Wang; Dong Yan; Guosheng Feng; Guangyu An
Journal:  BMC Cancer       Date:  2014-09-25       Impact factor: 4.430

9.  Rab27b is a potential predictor for metastasis and prognosis in colorectal cancer.

Authors:  Jun Bao; Yijiang Ni; Hui Qin; Li Xu; Zhijun Ge; Feng Zhan; Huijun Zhu; Jiabi Zhao; Xiaoli Zhou; Xiaojun Tang; Liming Tang
Journal:  Gastroenterol Res Pract       Date:  2014-12-16       Impact factor: 2.260

10.  Recommendations from the EGAPP Working Group: can testing of tumor tissue for mutations in EGFR pathway downstream effector genes in patients with metastatic colorectal cancer improve health outcomes by guiding decisions regarding anti-EGFR therapy?

Authors: 
Journal:  Genet Med       Date:  2013-02-21       Impact factor: 8.822
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  5 in total

1.  High-resolution MRI-based radiomics analysis to predict lymph node metastasis and tumor deposits respectively in rectal cancer.

Authors:  Yan-Song Yang; Feng Feng; Yong-Juan Qiu; Gui-Hua Zheng; Ya-Qiong Ge; Yue-Tao Wang
Journal:  Abdom Radiol (NY)       Date:  2020-09-17

Review 2.  Predictors and prognosticators for survival with Yttrium-90 radioembolization therapy for unresectable colorectal cancer liver metastasis.

Authors:  Meaghan S Dendy; Johannes M Ludwig; Hyun S Kim
Journal:  Oncotarget       Date:  2017-06-06

3.  A Novel Prognostic Model Incorporating Carcinoembryonic Antigen in 3-Week or Longer Postoperative Period for Stage III Colon Cancer: A Multicenter Retrospective Study.

Authors:  Jin Fan; Yanlong Liu; Xin Cai; Jingwen Wang; Rui Guo; Yuan Ji; Chao Li; Ye Xu; Xinxiang Li; Chundong Zhang; Rui Zhang; Ji Zhu; Sanjun Cai
Journal:  Front Oncol       Date:  2020-12-01       Impact factor: 6.244

4.  Site-Specific N-Linked Glycosylation Analysis of Human Carcinoembryonic Antigen by Sheathless Capillary Electrophoresis-Tandem Mass Spectrometry.

Authors:  Laura Pont; Valeriia Kuzyk; Fernando Benavente; Victoria Sanz-Nebot; Oleg A Mayboroda; Manfred Wuhrer; Guinevere S M Lageveen-Kammeijer
Journal:  J Proteome Res       Date:  2021-02-09       Impact factor: 4.466

5.  Prognostic Significance of Preoperative Serum Carcinoembryonic Antigen Varies with Lymph Node Metastasis Status in Colorectal Cancer.

Authors:  Jing Jia; MinZhe Li; Wenhao Teng; Lin Wang; Weidong Zang; Jun Xiao; Ying Chen
Journal:  J Oncol       Date:  2021-12-27       Impact factor: 4.375
  5 in total

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