Literature DB >> 27582415

Spatial cognition in mice and rats: similarities and differences in brain and behavior.

Vincent Hok1,2, Bruno Poucet3,4, Éléonore Duvelle5, Étienne Save1,2, Francesca Sargolini1,2,6.   

Abstract

The increasing use of mice models in cognitive tasks that were originally designed for rats raises crucial questions about cross-species comparison in the study of spatial cognition. The present review focuses on the major neuroethological differences existing between mice and rats, with particular attention given to the neurophysiological basis of space coding. While little difference is found in the basic properties of space representation in these two species, it appears that the stability of this representation changes more drastically over time in mice than in rats. We consider several hypotheses dealing with attentional, perceptual, and genetic aspects and offer some directions for future research that might help in deciphering hippocampal function in learning and memory processes. WIREs Cogn Sci 2016, 7:406-421. doi: 10.1002/wcs.1411 For further resources related to this article, please visit the WIREs website.
© 2016 Wiley Periodicals, Inc.

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Year:  2016        PMID: 27582415     DOI: 10.1002/wcs.1411

Source DB:  PubMed          Journal:  Wiley Interdiscip Rev Cogn Sci        ISSN: 1939-5078


  11 in total

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