Literature DB >> 27581192

Erratum to: Exploring the effects of coexisting amyloid in subcortical vascular cognitive impairment.

Elizabeth Dao1, Ging-Yuek Robin Hsiung2, Vesna Sossi3, Claudia Jacova4, Roger Tam5,6, Katie Dinelle7, John R Best1, Teresa Liu-Ambrose8,9.   

Abstract

Entities:  

Year:  2016        PMID: 27581192      PMCID: PMC5007817          DOI: 10.1186/s12883-016-0673-5

Source DB:  PubMed          Journal:  BMC Neurol        ISSN: 1471-2377            Impact factor:   2.474


× No keyword cloud information.

Erratum

After publication of the original article [1], it came to the authors’ attention that there were data entry errors in the following variables: age, sex, education, MOCA, WML volume, and ADAS-Cog. Changes have been made to Tables 1, 2, 3 and 4, to reflect the updated results, which are published in their correct version here. However, the authors note that the study conclusions have not changed.
Table 1

Descriptive characteristic

VariableMeanSD
Age71.737.91
Female Sex, No. (%)732
Education, No. (%)
 High school education627
 Trade or professional certificate or diploma29
 University education1464
MMSE (max. score 30)27.501.95
MOCA (max. score 30)23.322.08
WHR0.910.08
BMI26.954.78
PIB-positive, No. (%)627.27
Global PIB BPND 0.070.23
WML volume (mm3), n = 162004.402761.15
Cognitive Assessments
 ADAS-Cog (max. score 70)9.633.88
 Exit-25 (max. score 50)10.594.38
 Stroop CW-C, sec.61.4426.01
 Trails B-A, sec.50.5124.84
 Digits F-B, sec.3.232.79

SD Standard Deviation, MMSE Mini-Mental State Examination, MOCA Montreal Cognitive Assessment; WHR Waist-to-Hip Ratio, BMI Body Mass Index, ADAS-Cog Alzheimer’s Disease Assessment Scale – Cognitive subscale, Exit-25 Executive Interview Test, Stroop CW-W Stroop Color Words minus Stroop colored x’s, Trails B-A Trails B (numbers and letters) minus Trails A (numbers), Digits F-B Digits Forwards minus Digits Backwards

Table 2

Correlation matrix

PIB BPND AgeEducationAPOE ε4ADAS-CogMOCAEXIT 25DigitsStroopTrails
PIB BPND
Age-0.00
Education-0.23-0.39
APOE ε40.360.09-0.20
ADAS-Cog0.53*0.16-0.110.53*
MOCA-0.54*-0.200.06-0.11-0.45*
EXIT-250.130.20-0.200.250.49*-0.52*
Digits0.020.17-0.35-0.45*-0.300.13-0.04
Stroop0.17-0.060.02-0.110.27-0.290.340.04
Trails0.19-0.08-0.250.48*0.15-0.180.290.010.13

*significant at p ≤ 0.05

Table 3

Multiple linear regression models assessing the contribution of PIB retention on ADAS-Cog

Independent variablesR2 Adjusted R2 R2 ChangeUnstandardized B (Standard Error)Standardized β P- Value
Model 1
PIB BPND 0.280.24-9.09 (3.29)0.530.01
Model 2
Step 10.300.180.30
Age0.07 (0.11)0.140.54
Education0.41 (1.86)0.050.83
APOE ε44.30 (1.64)0.530.02
Step 20.440.310.15*
Age0.09 (0.10)0.180.37
Education1.15 (1.74)0.140.52
APOE ε43.20 (1.59)0.390.06
PIB BPND 7.23 (3.42)0.420.05

*significant at p ≤ 0.05

Table 4

Multiple linear regression models assessing the contribution of PIB retention on MOCA

Independent variablesR2 Adjusted R2 R2 ChangeUnstandardized B (Standard Error)Standardized β P- Value
Model 1
PIB BPND 0.290.26--5.00 (1.74)-0.540.01
Model 2
Step 10.05-0.110.05
Age-0.06 (0.07)-0.210.41
Education-0.22 (1.16)-0.050.85
APOE ε4-0.43 (1.02)-0.100.68
Step 20.370.220.32*
Age-0.07 (0.06)-0.280.20
Education-0.80 (0.99)-0.180.43
APOE ε40.44 (0.91)0.100.63
PIB BPND -5.71 (1.95)-0.620.01

*significant at p ≤ 0.05

Descriptive characteristic SD Standard Deviation, MMSE Mini-Mental State Examination, MOCA Montreal Cognitive Assessment; WHR Waist-to-Hip Ratio, BMI Body Mass Index, ADAS-Cog Alzheimer’s Disease Assessment Scale – Cognitive subscale, Exit-25 Executive Interview Test, Stroop CW-W Stroop Color Words minus Stroop colored x’s, Trails B-A Trails B (numbers and letters) minus Trails A (numbers), Digits F-B Digits Forwards minus Digits Backwards Correlation matrix *significant at p ≤ 0.05 Multiple linear regression models assessing the contribution of PIB retention on ADAS-Cog *significant at p ≤ 0.05 Multiple linear regression models assessing the contribution of PIB retention on MOCA *significant at p ≤ 0.05
  1 in total

1.  Exploring the effects of coexisting amyloid in subcortical vascular cognitive impairment.

Authors:  Elizabeth Dao; Ging-Yuek Robin Hsiung; Vesna Sossi; Claudia Jacova; Roger Tam; Katie Dinelle; John R Best; Teresa Liu-Ambrose
Journal:  BMC Neurol       Date:  2015-10-12       Impact factor: 2.474

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.