Literature DB >> 27581001

[Spinal epidural lipomatosis as a rare side effect in steroid-dependent Jo-1 antibody syndrome].

V S Schäfer1, W A Schmidt2, C Meybaum3, V Rosenkranz2, A Krause2.   

Abstract

Spinal epidural lipomatosis (SEL) of the thoracic and lumbar spine is a rare entity, which leads to compression of the spinal canal. The exact pathogenesis is still unknown. It most commonly occurs in patients with long-term exogenous or endogenous glucocorticoid excess or morbid obesity but there are also idiopathic forms. The symptoms depend on the severity of the SEL and can manifest as clinically asymptomatic, non-specific back pain, radiculopathy up to spinal cord compression. The diagnosis is usually achieved by magnetic resonance imaging (MRI) of the affected spinal segments. The treatment varies between discontinuation of glucocorticoids, weight reduction up to multisegmental decompressive laminectomy. The following case report presents the findings of SEL in a patient with steroid-dependent Jo-1 antibody syndrome and provides a current literature review on this rare disease.

Entities:  

Keywords:  Glucocorticoids; Jo-1 antibody syndrome; Side effect; Spinal epidural lipomatosis

Mesh:

Substances:

Year:  2016        PMID: 27581001     DOI: 10.1007/s00393-016-0173-4

Source DB:  PubMed          Journal:  Z Rheumatol        ISSN: 0340-1855            Impact factor:   1.372


  21 in total

1.  Symptomatic spinal epidural lipomatosis after local epidural corticosteroid injections: case report.

Authors:  D I Sandberg; M H Lavyne
Journal:  Neurosurgery       Date:  1999-07       Impact factor: 4.654

Review 2.  [Spinal epidural lipomatosis].

Authors:  J Artner; F Leucht; B Cakir; H Reichel; F Lattig
Journal:  Orthopade       Date:  2012-11       Impact factor: 1.087

Review 3.  Epidural lipomatosis in steroid-treated patients.

Authors:  R G Fessler; D L Johnson; F D Brown; R K Erickson; S A Reid; L Kranzler
Journal:  Spine (Phila Pa 1976)       Date:  1992-02       Impact factor: 3.468

4.  [Steroid-induced spinal epidural lipomatosis in pediatric patients].

Authors:  J Möller; H J Girschick; G Hahn; F Pessler
Journal:  Z Rheumatol       Date:  2010-07       Impact factor: 1.372

Review 5.  Symptomatic lumbar epidural lipomatosis in a normal male. A unique case report.

Authors:  D A Bednar; S I Esses; W Kucharczyk
Journal:  Spine (Phila Pa 1976)       Date:  1990-01       Impact factor: 3.468

6.  Lumbar epidural lipomatosis: the "Y" sign of thecal sac compression.

Authors:  M J Kuhn; H T Youssef; T L Swan; L C Swenson
Journal:  Comput Med Imaging Graph       Date:  1994 Sep-Oct       Impact factor: 4.790

Review 7.  Spinal epidural lipomatosis: two new idiopathic cases and a review of the literature.

Authors:  J D Stern; D J Quint; T A Sweasey; J T Hoff
Journal:  J Spinal Disord       Date:  1994-08

8.  Spinal epidural lipomatosis in a human immunodeficiency virus-positive patient receiving steroids and protease inhibitor therapy.

Authors:  J R Ebright; M A Stellini; A C Tselis
Journal:  Clin Infect Dis       Date:  2001-02-20       Impact factor: 9.079

9.  Symptomatic spinal epidural lipomatosis after a single local epidural steroid injection.

Authors:  Chung Hong Tok; Shaleen Kaur; Afshin Gangi
Journal:  Cardiovasc Intervent Radiol       Date:  2010-09-22       Impact factor: 2.740

10.  Idiopathic and glucocorticoid-induced spinal epidural lipomatosis.

Authors:  S F Haddad; P W Hitchon; J C Godersky
Journal:  J Neurosurg       Date:  1991-01       Impact factor: 5.115

View more
  1 in total

Review 1.  Spinal Epidural Lipomatosis: A Review of Pathogenesis, Characteristics, Clinical Presentation, and Management.

Authors:  Keonhee Kim; Joseph Mendelis; Woojin Cho
Journal:  Global Spine J       Date:  2018-08-13
  1 in total

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