Literature DB >> 27580851

Lymph node management in the treatment of oral cancer: Analysis of a standardized approach.

Steffen Koerdt1, Jonas Röckl2, Niklas Rommel2, Thomas Mücke2, Klaus-Dietrich Wolff2, Marco R Kesting2.   

Abstract

INTRODUCTION: A supraomohyoid neck dissection (SOHND) is part of the surgical management of patients with oral cancer, even in the absence of clinical or radiographic evidence of neck disease. We have investigated a standardized approach to the management of cervical lymph nodes, in patients with a primary oral cancer. A modified surgical technique has been presented and a clinical algorithm has been described and evaluated.
MATERIALS AND METHODS: SOHND was performed either uni- or bi-laterally. In cases of positive nodes in levels II or III, the dissection was extended in terms of a modified radical neck dissection (MRND) and a SOHND was performed contralaterally.
RESULTS: 112 patients were included. 42% had lymph node metastases in any level. Overall, lymph node metastases were found in 2.8% of all examined nodes. Most metastases (34.6%) occurred in level Ib. 12.6% were located in level IIb. No metastases could be detected in levels IV and V. No statistically significant difference could be shown with regard to T-stage, location, or co-factors as gender and age. DISCUSSION: SOHND is the gold-standard in patients with no preoperative evidence of lymph node metastases. The presented algorithm is able to facilitate dissection and histological analysis and might improve the surgical care in current treatment concepts. The extension to an MRND facilitates the identification of patients in need of adjuvant therapy.
Copyright © 2016 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Lymphadenectomy; Mouth neoplasms; Neck dissection; Oral cancer; Squamous cell carcinoma

Mesh:

Year:  2016        PMID: 27580851     DOI: 10.1016/j.jcms.2016.08.002

Source DB:  PubMed          Journal:  J Craniomaxillofac Surg        ISSN: 1010-5182            Impact factor:   2.078


  8 in total

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Authors:  Jan Oliver Voss; Lea Freund; Felix Neumann; Friedrich Mrosk; Kerstin Rubarth; Kilian Kreutzer; Christian Doll; Max Heiland; Steffen Koerdt
Journal:  Clin Oral Investig       Date:  2022-07-27       Impact factor: 3.606

2.  How is neck dissection performed in Oral and Maxillofacial Surgery? Results of a representative nationwide survey among university and non-university hospitals in Germany.

Authors:  Andreas Pabst; Daniel G E Thiem; Elisabeth Goetze; Alexander K Bartella; Michael T Neuhaus; Jürgen Hoffmann; Alexander-N Zeller
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3.  Galectin 3 expression in regional lymph nodes and lymph node metastases of oral squamous cell carcinomas.

Authors:  Falk Wehrhan; Maike Büttner-Herold; Luitpold Distel; Jutta Ries; Patrick Moebius; Raimund Preidl; Carol I Geppert; Friedrich W Neukam; Marco Kesting; Manuel Weber
Journal:  BMC Cancer       Date:  2018-08-16       Impact factor: 4.430

4.  Therapeutic Targeting of MYC in Head and Neck Squamous Cell Carcinoma.

Authors:  Shuo Liu; Zhen Qin; Yaqing Mao; Wenbo Zhang; Yujia Wang; Lingfei Jia; Xin Peng
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5.  Cervical level IIb metastases in squamous cell carcinoma of the oral cavity: a systematic review and meta-analysis.

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6.  Extent of neck dissection for patients with clinical N1 oral cancer.

Authors:  Yasumasa Kakei; Hirokazu Komatsu; Tsutomu Minamikawa; Takumi Hasegawa; Masanori Teshima; Hirotaka Shinomiya; Naoki Otsuki; Ken-Ichi Nibu; Masaya Akashi
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7.  Predictive modelling of level IIb lymph node metastasis in oral squamous cell carcinoma.

Authors:  Hyunwoo Yang; Nak-Hoon Son; Sung Hwa Lee; Dongwook Kim; Hyung Jun Kim; In-Ho Cha; Woong Nam
Journal:  Sci Rep       Date:  2021-09-02       Impact factor: 4.379

8.  Neoadjuvant Immunotherapy of Oral Squamous Cell Carcinoma: Case Report and Assessment of Histological Response.

Authors:  Manuel Olmos; Jacek Glajzer; Tjark-Ole Büntemeyer; Gesche Frohwitter; Jutta Ries; Markus Eckstein; Markus Hecht; Rainer Lutz; Marco Rainer Kesting; Manuel Weber
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  8 in total

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