Literature DB >> 27580567

V2A2lidating TRP channel heteromers.

Michael Jm Fischer1, J Michael Edwardson2.   

Abstract

Transient receptor potential (TRP) ion channels play a key role in sensing environmental and endogenous stimuli. Among sensory neurons, different TRP channels are widely expressed, and their expression profiles overlap. Although many TRP channels are homotetramers, we have shown that a functional tetrameric TRP channel can contain two types of monomers.

Entities:  

Keywords:  TRPA1; TRPV1; concatemer; dimer; heteromer; pain

Year:  2014        PMID： 27580567      PMCID： PMC4972508          DOI： 10.4161/temp.29548

Source DB:  PubMed          Journal:  Temperature (Austin)        ISSN： 2332-8940


  7 in total

1.  Contribution of TRPV1-TRPA1 interaction to the single channel properties of the TRPA1 channel.

Authors:  Alexander Staruschenko; Nathaniel A Jeske; Armen N Akopian
Journal:  J Biol Chem       Date:  2010-03-15       Impact factor: 5.157

2.  The capsaicin receptor: a heat-activated ion channel in the pain pathway.

Authors:  M J Caterina; M A Schumacher; M Tominaga; T A Rosen; J D Levine; D Julius
Journal:  Nature       Date:  1997-10-23       Impact factor: 49.962

3.  Ligand stoichiometry of the cold- and menthol-activated channel TRPM8.

Authors:  Annelies Janssens; Thomas Voets
Journal:  J Physiol       Date:  2011-08-30       Impact factor: 5.182

4.  Evidence for the formation of heteromultimeric potassium channels in Xenopus oocytes.

Authors:  E Y Isacoff; Y N Jan; L Y Jan
Journal:  Nature       Date:  1990-06-07       Impact factor: 49.962

5.  Heteromeric heat-sensitive transient receptor potential channels exhibit distinct temperature and chemical response.

Authors:  Wei Cheng; Fan Yang; Shuang Liu; Craig K Colton; Chunbo Wang; Yuanyuan Cui; Xu Cao; Michael X Zhu; Changsen Sun; KeWei Wang; Jie Zheng
Journal:  J Biol Chem       Date:  2011-12-19       Impact factor: 5.157

6.  C-terminal dimerization activates the nociceptive transduction channel transient receptor potential vanilloid 1.

Authors:  Shu Wang; Huai-hu Chuang
Journal:  J Biol Chem       Date:  2011-09-16       Impact factor: 5.157

7.  Direct evidence for functional TRPV1/TRPA1 heteromers.

Authors:  Michael J M Fischer; Dilshan Balasuriya; Pia Jeggle; Tom A Goetze; Peter A McNaughton; Peter W Reeh; J Michael Edwardson
Journal:  Pflugers Arch       Date:  2014-03-19       Impact factor: 3.657
  7 in total
  2 in total

1.  Inflammation up-regulates cochlear expression of TRPV1 to potentiate drug-induced hearing loss.

Authors:  Meiyan Jiang; Hongzhe Li; Anastasiya Johnson; Takatoshi Karasawa; Yuan Zhang; William B Meier; Farshid Taghizadeh; Allan Kachelmeier; Peter S Steyger
Journal:  Sci Adv       Date:  2019-07-17       Impact factor: 14.136

2.  Polydisperse molecular architecture of connexin 26/30 heteromeric hemichannels revealed by atomic force microscopy imaging.

Authors:  Pamela A Naulin; Benjamin Lozano; Christian Fuentes; Yu Liu; Carla Schmidt; Jorge E Contreras; Nelson P Barrera
Journal:  J Biol Chem       Date:  2020-09-04       Impact factor: 5.157
  2 in total

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