Complexity of virus-vector interactions.

The inter-relationships among viruses, vectors and vertebrate hosts are complex and dynamic and shaped by biotic (e.g., viral strain, vector genetics, host susceptibility) and abiotic (e.g., temperature, rainfall, human land use) factors. It is anticipated that changes in climate, as predicted by the most recent Report of the Intergovernmental Panel on Climate Change, will result in landscape changes and consequent changes in spatiotemporal patterns of arbovirus transmission. To anticipate evolving patterns of virus activity in a dynamically changing environment, it is important to understand how interconnectedness of mosquito and virus biology together with climate influence arbovirus transmission intensity. Vector competence, survivorship, and feeding behavior, among other aspects of vectorial capacity are intrinsically important to estimate risk and design control approaches. Copyright Â