Literature DB >> 27579651

Genomic Classification in Acute Myeloid Leukemia.

Elli Papaemmanuil, Hartmut Döhner, Peter J Campbell.   

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Year:  2016        PMID: 27579651     DOI: 10.1056/NEJMc1608739

Source DB:  PubMed          Journal:  N Engl J Med        ISSN: 0028-4793            Impact factor:   91.245


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Authors:  Jarno L Kivioja; Angeliki Thanasopoulou; Ashwini Kumar; Mika Kontro; Bhagwan Yadav; Muntasir M Majumder; Komal K Javarappa; Samuli Eldfors; Juerg Schwaller; Kimmo Porkka; Caroline A Heckman
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2.  Molecular characterization of acute myeloid leukemia patients who relapse more than 3 years after diagnosis: an exome sequencing study of 31 patients.

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Review 4.  The evidence framework for precision cancer medicine.

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Review 7.  The emergence of acid ceramidase as a therapeutic target for acute myeloid leukemia.

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8.  Gilteritinib is a clinically active FLT3 inhibitor with broad activity against FLT3 kinase domain mutations.

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9.  A phase 1/2 study of the oral FLT3 inhibitor pexidartinib in relapsed/refractory FLT3-ITD-mutant acute myeloid leukemia.

Authors:  Catherine C Smith; Mark J Levis; Olga Frankfurt; John M Pagel; Gail J Roboz; Richard M Stone; Eunice S Wang; Paul L Severson; Brian L West; Mai H Le; Sabine Kayser; Bao Lam; Henry H Hsu; Chao Zhang; Gideon Bollag; Alexander E Perl
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10.  Genetic heterogeneity of cytogenetically normal AML with mutations of CEBPA.

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