Literature DB >> 27579117

Successful vaginal birth after caesarean section in patient with Ehler-Danlos syndrome type 2.

Hemant Maraj1, Michelle Mohajer1, Deepannita Bhattacharjee2.   

Abstract

We present the case of a 31-year-old woman with Ehler-Danlos syndrome (EDS) type 2. She had a previous caesarean section and went on to have an uncomplicated vaginal birth in her last pregnancy. To our knowledge, this is the first case of a successful vaginal birth after caesarean section in a patient with EDS. EDS is a multisystem disorder involving a genetic defect in collagen and connective-tissue synthesis and structure. It is a heterogeneous group of 11 different inherited disorders. Obstetric complications in these patients include miscarriages, stillbirths, premature rupture of the membranes, preterm labour, uterine prolapse, uterine rupture and severe postpartum haemorrhage. There has been much controversy over the appropriate mode of delivery. Abdominal deliveries are complicated by delayed wound healing and increased perioperative blood loss. Vaginal deliveries may be complicated by tissue friability causing extensive perineal tears, pelvic floor and bladder lesions. Our case highlights that in specific, controlled situations it is possible to have a vaginal delivery even after previous caesarean section in patients with EDS.

Entities:  

Keywords:  clinical genetics; complications; high-risk pregnancy; rheumatology

Year:  2011        PMID: 27579117      PMCID: PMC4989637          DOI: 10.1258/om.2011.100069

Source DB:  PubMed          Journal:  Obstet Med        ISSN: 1753-495X


  9 in total

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  9 in total

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