| Literature DB >> 27579058 |
Abstract
Diabetes insipidus is an uncommon condition with various aetiologies. Recent research has uncovered new mechanisms underlying the syndrome. Careful attention to management is essential in pregnant women to avoid serious complications. Diabetes insipidus in pregnancy may be due to relative reduction in secretion of AVP from the posterior pituitary (cranial DI), increase in breakdown of AVP by placental cystine aminopeptidase with vasopressinase activity, or resistance of the rental tubules to AVP (nephrogenic DI).Entities:
Keywords: aquaporin; dDAVP; diabetes insipidus; pregnancy; vasopressin
Year: 2009 PMID: 27579058 PMCID: PMC4989665 DOI: 10.1258/om.2009.090027
Source DB: PubMed Journal: Obstet Med ISSN: 1753-495X