Literature DB >> 27576461

Inflammatory properties of antibiotic-treated bacteria.

Andrea J Wolf1,2, George Y Liu2,3, David M Underhill4,2.   

Abstract

Antibiotics have proven to be enormously effective tools in combating infectious diseases. A common roadblock to the effective use of antibiotics is the development of antibiotic resistance. We have recently observed that the very mechanism by which methicillin-resistant Staphylococcus aureus (MRSA) becomes antibiotic resistant causes the organism to be more inflammatory to innate immune cells. In this review, we offer some thoughts on the ways in which antibiotics have been observed to influence immune responses to bacteria. © Society for Leukocyte Biology.

Entities:  

Keywords:  Staphylococcus aureus; autolysis; peptidoglycan; β-lactam

Mesh:

Substances:

Year:  2016        PMID: 27576461      PMCID: PMC5166437          DOI: 10.1189/jlb.4MR0316-153RR

Source DB:  PubMed          Journal:  J Leukoc Biol        ISSN: 0741-5400            Impact factor:   4.962


  76 in total

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4.  Antibiotic-induced modification of Bacteroides fragilis and its susceptibility to phagocytosis by human polymorphonuclear leukocytes.

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6.  Nafcillin enhances innate immune-mediated killing of methicillin-resistant Staphylococcus aureus.

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7.  Failure to induce IFN-β production during Staphylococcus aureus infection contributes to pathogenicity.

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9.  The surface protein Lmo1941 with LysM domain influences cell wall structure and susceptibility of Listeria monocytogenes to cephalosporins.

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Journal:  J Biol Chem       Date:  2020-06-30       Impact factor: 5.157

Review 2.  Peptidoglycan recognition by the innate immune system.

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3.  Thymidine starvation promotes c-di-AMP-dependent inflammation during pathogenic bacterial infection.

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Review 5.  Antibiotic Treatment, Mechanisms for Failure, and Adjunctive Therapies for Infections by Group A Streptococcus.

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  5 in total

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