| Literature DB >> 27576461 |
Andrea J Wolf1,2, George Y Liu2,3, David M Underhill4,2.
Abstract
Antibiotics have proven to be enormously effective tools in combating infectious diseases. A common roadblock to the effective use of antibiotics is the development of antibiotic resistance. We have recently observed that the very mechanism by which methicillin-resistant Staphylococcus aureus (MRSA) becomes antibiotic resistant causes the organism to be more inflammatory to innate immune cells. In this review, we offer some thoughts on the ways in which antibiotics have been observed to influence immune responses to bacteria. © Society for Leukocyte Biology.Entities:
Keywords: Staphylococcus aureus; autolysis; peptidoglycan; β-lactam
Mesh:
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Year: 2016 PMID: 27576461 PMCID: PMC5166437 DOI: 10.1189/jlb.4MR0316-153RR
Source DB: PubMed Journal: J Leukoc Biol ISSN: 0741-5400 Impact factor: 4.962