| Literature DB >> 27575472 |
Li Yang1, Yu-Bo Zhang1, Li-Feng Chen1, Neng-Hua Chen1, Zhong-Nan Wu1, Si-Qi Jiang1, Lin Jiang1, Guo-Qiang Li1, Yao-Lan Li2, Guo-Cai Wang3.
Abstract
Nine new labdane diterpenoids (1-9) were isolated from the aerial parts of Croton laui, along with eight known analogues (10-17). Their structures were identified on the basis of the spectral data (IR, UV, HRESIMS, 1D and 2D NMR), and the structure of 8 was confirmed by single crystal X-ray diffraction analyses. In addition, compounds 1, 4, 7, 8, and 14 showed weak anti-inflammatory activities in LPS-stimulated RAW 264.7 cells.Entities:
Keywords: Anti-inflammatory activity; Croton laui; Labdane diterpenoid
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Year: 2016 PMID： 27575472 DOI： 10.1016/j.bmcl.2016.08.052
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823