Literature DB >> 2757505

The treatment of achalasia. A current perspective.

L Sauer1, C A Pellegrini, L W Way.   

Abstract

We analyzed the course of 79 adult patients treated for achalasia between 1977 and 1988. Sixty-six patients (84%) had pneumatic dilatation as the primary therapy. Fifty-three patients (80%) had immediate improvement in swallowing. Three patients required immediate redilatation, 2 developed pulmonary aspiration, and 8 (12%) suffered esophageal perforation. Esophageal perforation was treated by closure plus Heller's myotomy in 3 patients, closure only in 3, chest tube in 1, and antibiotics and nasogastric suction in 1. At 4 years' follow-up, 50% of patients who had dilatation remained asymptomatic, 30% had symptoms of gastroesophageal reflux, and 20% had persistent dysphagia. Eight Heller myotomies were performed, with excellent results in 7 and 1 postoperative death from respiratory failure. Seven additional patients with disabling esophageal symptoms after multiple operations for achalasia were ultimately treated by esophagectomy (n = 5), hemigastrectomy and Roux-en-Y gastrojejunostomy (n = 1), and repeated myotomy (n = 1). All recovered and are able to eat solid food. Thus, our experience indicates that pneumatic dilatation remains unperfected (ie, the line between undertreatment and overtreatment is finer than generally recognized), and unless improvements can be made, the role for surgery may need to be reexpanded.

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Mesh:

Year:  1989        PMID: 2757505     DOI: 10.1001/archsurg.1989.01410080061009

Source DB:  PubMed          Journal:  Arch Surg        ISSN: 0004-0010


  20 in total

1.  Management of esophageal perforation after pneumatic dilation for achalasia.

Authors:  D R Hunt; V L Wills; B Weis; J O Jorgensen; D J DeCarle; I J Coo
Journal:  J Gastrointest Surg       Date:  2000 Jul-Aug       Impact factor: 3.452

2.  Prevention of post-operative leak following laparoscopic Heller myotomy.

Authors:  Kelly R Finan; David Renton; Catherine C Vick; Mary T Hawn
Journal:  J Gastrointest Surg       Date:  2008-09-10       Impact factor: 3.452

3.  Reproducibility of ambulatory esophageal pH monitoring in the aperistaltic esophagus.

Authors:  J P Shoenut; A B Mieflikier; T A Aldor; C S Yaffe; D J Goldenberg
Journal:  Dysphagia       Date:  1996       Impact factor: 3.438

4.  Individual prediction of response to pneumatic dilation in patients with achalasia.

Authors:  J Ponce; V Garrigues; V Pertejo; T Sala; J Berenguer
Journal:  Dig Dis Sci       Date:  1996-11       Impact factor: 3.199

5.  Thoracoscopic Hellers myotomy for oesophageal achalasia.

Authors:  S Rea; C J Kelly; P J Broe
Journal:  Ir J Med Sci       Date:  1999 Jan-Mar       Impact factor: 1.568

6.  Gasless laparoscopic esophagomyotomy.

Authors:  D J Azurin; L S Go; A L Schuricht
Journal:  Surg Endosc       Date:  1995-10       Impact factor: 4.584

7.  Outcome after perforation sustained during pneumatic dilatation for achalasia.

Authors:  H M Schwartz; C E Cahow; M Traube
Journal:  Dig Dis Sci       Date:  1993-08       Impact factor: 3.199

8.  Forceful dilatation under endoscopic control in the treatment of achalasia: a randomised trial of pneumatic versus metallic dilator.

Authors:  F Mearin; J R Armengol; L Chicharro; M Papo; A Balboa; J R Malagelada
Journal:  Gut       Date:  1994-10       Impact factor: 23.059

9.  Surgical treatment of achalasia: a retrospective comparative study.

Authors:  A Picciocchi; G Cardillo; D D'Ugo; G Castrucci; L Mascellari; P Granone
Journal:  Surg Today       Date:  1993       Impact factor: 2.549

10.  Importance of preoperative and postoperative pH monitoring in patients with esophageal achalasia.

Authors:  M G Patti; M Arcerito; J Tong; A Wang; C V Feo; S J Mulvihill; L W Way
Journal:  J Gastrointest Surg       Date:  1997 Nov-Dec       Impact factor: 3.452

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