Maryam Abbasian1, Mehri Delvarianzadeh2, Hossein Ebrahimi3, Farideh Khosravi4. 1. School of Medicine, Shahroud University of Medical Sciences, 7th Sq, Shahroud, Iran. Electronic address: abbasian39@yahoo.com. 2. School of public Health, Shahroud University of Medical Sciences, Basij Sq, Shahroud, Iran. Electronic address: delvarianzadeh_mehri@yahoo.com. 3. Randomized Controlled Trial Research Center, Shahroud University of Medical Sciences, 7th Sq, Shahroud, Iran. Electronic address: Ebrahimi@shmu.ac.ir. 4. Department of Biostatistics, Occupational and Environmental Health Research Center, Shahroud University of Medical Sciences, 7th Sq, Shahroud, Iran. Electronic address: faridehkhosravi50@yahoo.com.
Abstract
AIMS: This study aimed to compare the serum lipids ratio in staff with and without metabolic syndrome (MetS) who were working in Shahroud University of Medical Sciences. METHODS: This case-control study was conducted in 2015 on 499 personnel aged 30-60 years old. ATP III criteria were used to diagnose patients with MetS. The data were analyzed by using logistic regression and ROC curve. RESULTS: Mean lipid ratio was higher in individuals having the MetS in both sexes compared with those without. In addition, the mean levels of lipid ratios significantly increased with increasing number of MetS components in both sexes. Also it could be concluded that TG/HDL-C ratio is the best marker for the diagnosis of MetS in men and women. Moreover, the cut-off point for the TG/HDL-C was 2.86 in women and 4.03 in men. It was found that for any unit of increases in the TG/HDL-C, the risk of developing the MetS will increase by 2.12 times. CONCLUSIONS: TG/HDL-C ratio is found to be the best clinical marker for the diagnosis of MetS compare with other lipid ratios, therefore it is recommended to be used as a feasible tool to identify individuals with MetS risk.
AIMS: This study aimed to compare the serum lipids ratio in staff with and without metabolic syndrome (MetS) who were working in Shahroud University of Medical Sciences. METHODS: This case-control study was conducted in 2015 on 499 personnel aged 30-60 years old. ATP III criteria were used to diagnose patients with MetS. The data were analyzed by using logistic regression and ROC curve. RESULTS: Mean lipid ratio was higher in individuals having the MetS in both sexes compared with those without. In addition, the mean levels of lipid ratios significantly increased with increasing number of MetS components in both sexes. Also it could be concluded that TG/HDL-C ratio is the best marker for the diagnosis of MetS in men and women. Moreover, the cut-off point for the TG/HDL-C was 2.86 in women and 4.03 in men. It was found that for any unit of increases in the TG/HDL-C, the risk of developing the MetS will increase by 2.12 times. CONCLUSIONS:TG/HDL-C ratio is found to be the best clinical marker for the diagnosis of MetS compare with other lipid ratios, therefore it is recommended to be used as a feasible tool to identify individuals with MetS risk.
Authors: Małgorzata Kałużna; Magdalena Czlapka-Matyasik; Pola Kompf; Jerzy Moczko; Katarzyna Wachowiak-Ochmańska; Adam Janicki; Karolina Samarzewska; Marek Ruchała; Katarzyna Ziemnicka Journal: Ther Adv Endocrinol Metab Date: 2022-01-10 Impact factor: 3.565