Literature DB >> 27574261

Microfracture technique versus carbon fibre rod implantation for treatment of knee articular cartilage lesions.

U Dasar1, S Gursoy2, M Akkaya2, O Algin3, C Isik4, M Bozkurt4.   

Abstract

PURPOSE: To compare the microfracture technique with carbon fibre rod implantation for treatment of knee articular cartilage lesions.
METHODS: 10 men and 30 women aged 22 to 56 (mean, 37.4) years underwent microfracture (n=20) or carbon fibre rod implantation (n=20) for International Cartilage Repair Society grade 3 to 4 knee articular cartilage lesions after a mean of 12.2 months of viscosupplementation and physiotherapy. Clinical outcome at 6 and 12 months was assessed using the Tegner-Lysholm score and modified Cincinnati score. Magnetic resonance imaging (MRI) outcome at 12 months was assessed by a radiologist. The modified magnetic resonance observation of cartilage repair tissue (MOCART) score was evaluated.
RESULTS: The 2 groups were comparable in terms of age, body mass index, lesion location, lesion size, duration of symptoms, and coexisting pathology. The microfracture group had a higher preoperative Tegner-Lysholm score (39.4±7.3 vs. 34.4±4.9, p=0.015) and modified Cincinnati score (36.4±7.2 vs. 30.4±4.0, p=0.002) than the carbon fibre rod group. At 12 months, change in both scores was significant within each group (p<0.001) and was higher in the microfracture than carbon fibre rod group (p<0.001). MRI showed minimal regenerative tissue. Lobulation, oedema, and hypertrophy were more commonly found in the regeneration tissue after carbon fibre rod implantation than microfracture. At 12 months, the MOCART score was higher in the microfracture than carbon fibre rod group (59 vs. 47, p<0.001).
CONCLUSION: Microfracture is superior to carbon fibre rod implantation in terms of clinical and radiological outcome.

Entities:  

Keywords:  arthroplasty, subchondral; cartilage, articular; magnetic resonance imaging

Mesh:

Substances:

Year:  2016        PMID: 27574261     DOI: 10.1177/1602400214

Source DB:  PubMed          Journal:  J Orthop Surg (Hong Kong)        ISSN: 1022-5536            Impact factor:   1.118


  5 in total

1.  Microfracture for cartilage repair in the knee: a systematic review of the contemporary literature.

Authors:  Patrick Orth; Liang Gao; Henning Madry
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2019-01-18       Impact factor: 4.342

Review 2.  Fibrous Systems as Potential Solutions for Tendon and Ligament Repair, Healing, and Regeneration.

Authors:  Chiara Rinoldi; Ewa Kijeńska-Gawrońska; Ali Khademhosseini; Ali Tamayol; Wojciech Swieszkowski
Journal:  Adv Healthc Mater       Date:  2021-02-12       Impact factor: 9.933

3.  Decrease of miR-195 Promotes Chondrocytes Proliferation and Maintenance of Chondrogenic Phenotype via Targeting FGF-18 Pathway.

Authors:  Yong Wang; Tao Yang; Yadong Liu; Wei Zhao; Zhen Zhang; Ming Lu; Weiguo Zhang
Journal:  Int J Mol Sci       Date:  2017-05-04       Impact factor: 5.923

4.  A 3D-Printed PLCL Scaffold Coated with Collagen Type I and Its Biocompatibility.

Authors:  Yong He; Wei Liu; Lianxiong Guan; Jielin Chen; Li Duan; Zhaofeng Jia; Jianghong Huang; Wencui Li; Jianquan Liu; Jianyi Xiong; Lijun Liu; Daping Wang
Journal:  Biomed Res Int       Date:  2018-02-28       Impact factor: 3.411

Review 5.  Advances of Stem Cell-Laden Hydrogels With Biomimetic Microenvironment for Osteochondral Repair.

Authors:  Bingbing Xu; Jing Ye; Fu-Zhen Yuan; Ji-Ying Zhang; You-Rong Chen; Bao-Shi Fan; Dong Jiang; Wen-Bo Jiang; Xing Wang; Jia-Kuo Yu
Journal:  Front Bioeng Biotechnol       Date:  2020-03-31
  5 in total

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