Literature DB >> 2757420

Influence of site of origin and mucin production on survival in ampullary carcinoma.

P J Dawson1, M M Connolly.   

Abstract

We studied a series of 26 cases of carcinoma of the ampulla of Vater. There were 24 adenocarcinomas and two neuroendocrine tumors. Histologically the carcinomas could be divided into tumors arising from periampullary duodenal mucosa and those arising within the ampulla. True ampullary tumors had a significantly better 5-year survival rate (p = 0.028) than periampullary tumors. The type of mucin produced was investigated histochemically. Patients with true ampullary tumors producing predominantly sialomucins had a better prognosis than those with tumors secreting sulphated mucins (p = 0.045), but the numbers were small. We hypothesize that the most favorable type of ampullary carcinoma arises from biliary-type epithelium within the ampulla.

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Year:  1989        PMID: 2757420      PMCID: PMC1357824          DOI: 10.1097/00000658-198908000-00006

Source DB:  PubMed          Journal:  Ann Surg        ISSN: 0003-4932            Impact factor:   12.969


  23 in total

1.  Survival in 1001 patients with carcinoma of the pancreas.

Authors:  M M Connolly; P J Dawson; F Michelassi; A R Moossa; F Lowenstein
Journal:  Ann Surg       Date:  1987-09       Impact factor: 12.969

2.  Histochemical procedures for the simultaneous visualization of sialic acid, its side chain O-acyl variants and O-sulphate ester.

Authors:  P E Reid; D A Owen; C W Ramey; W L Dunn; M G Clay; E A Jones
Journal:  Histochem J       Date:  1985-01

3.  Histochemical staining of sulphated and non-sulphated sialomucin in intestinal epithelium: practical difficulties associated with the KOH-AB 1.0-PAPS method.

Authors:  S J Buk; M I Filipe
Journal:  Histochem J       Date:  1986-10

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Authors:  A L Cubilla; P J Fitzgerald
Journal:  Monogr Pathol       Date:  1980

5.  Twenty-two year experience with periampullary carcinoma at Memorial Sloan-Kettering Cancer Center.

Authors:  J A Williams; A Cubilla; B J Maclean; J G Fortner
Journal:  Am J Surg       Date:  1979-11       Impact factor: 2.565

6.  Carcinoma of the ampulla of Vater.

Authors:  D H Hayes; J S Bolton; G W Willis; J C Bowen
Journal:  Ann Surg       Date:  1987-11       Impact factor: 12.969

7.  Results of surgical treatment of periampullary tumors: a thirty-five-year experience.

Authors:  R Y Tarazi; R E Hermann; D P Vogt; S O Hoerr; C B Esselstyn; A M Cooperman; E Steiger; S Grundfest
Journal:  Surgery       Date:  1986-10       Impact factor: 3.982

8.  Carcinoma of the ampulla of vater. A clinicopathologic study and pathologic staging of 109 cases of carcinoma and 5 cases of adenoma.

Authors:  K Yamaguchi; M Enjoji
Journal:  Cancer       Date:  1987-02-01       Impact factor: 6.860

9.  Pancreatoduodenectomy for resectable malignant periampullary tumors.

Authors:  J M Kellum; J Clark; H H Miller
Journal:  Surg Gynecol Obstet       Date:  1983-10

10.  Carcinoma of the ampulla of Vater.

Authors:  R A Knox; R D Kingston
Journal:  Br J Surg       Date:  1986-01       Impact factor: 6.939

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  5 in total

1.  Carcinoma of the ampulla of Vater: prognostic factors after curative surgery: a series of 45 cases.

Authors:  A Dorandeu; J L Raoul; F Siriser; N Leclercq-Rioux; M Gosselin; E D Martin; M P Ramée; B Launois
Journal:  Gut       Date:  1997-03       Impact factor: 23.059

2.  Human cell line from an adenocarcinoma of the ampulla of Vater.

Authors:  M L Frazier; N Brown; S Pathak; B Mackay; K Cleary; M Olive; D R Byrd; D B Evans; B Levin
Journal:  In Vitro Cell Dev Biol       Date:  1992-03

3.  Prognostic factors for ampullary adenocarcinomas: tumor stage, tumor histology, tumor location, immunohistochemistry and microsatellite instability.

Authors:  Fausto Sessa; Daniela Furlan; Clementina Zampatti; Ileana Carnevali; Francesca Franzi; Carlo Capella
Journal:  Virchows Arch       Date:  2007-07-26       Impact factor: 4.064

4.  Neoplasia of the ampulla of Vater. Ki-ras and p53 mutations.

Authors:  A Scarpa; P Capelli; G Zamboni; T Oda; K Mukai; F Bonetti; G Martignoni; C Iacono; G Serio; S Hirohashi
Journal:  Am J Pathol       Date:  1993-04       Impact factor: 4.307

5.  Signet-ring cell carcinoma of the distal common bile duct: report of a case.

Authors:  Hyung Jun Kwon; Ghil-Suk Yoon; Yong Chul Kwon; Sang Geol Kim; Ji Yun Jeong
Journal:  Korean J Pathol       Date:  2014-08-26
  5 in total

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