Literature DB >> 27572817

Curative potential of allogeneic hematopoietic stem cell transplant in type 1 diabetes.

Kristen E McCabe1, Allison J Pollock1, Jennifer L Rehm1, Kenneth B DeSantes1.   

Abstract

The mainstay of treatment for type 1 diabetes (T1D) is exogenous insulin. Here, we report a case in which exogenous insulin requirements were eliminated after an allogeneic hematopoietic stem cell transplant for aplastic anemia in a pediatric patient recently diagnosed with T1D, and explore the validity of this approach compared with current treatments.
© 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  aplastic anemia; autoimmune; transplant; type 1 diabetes

Mesh:

Year:  2016        PMID: 27572817      PMCID: PMC5955001          DOI: 10.1111/pedi.12430

Source DB:  PubMed          Journal:  Pediatr Diabetes        ISSN: 1399-543X            Impact factor:   4.866


  13 in total

1.  Impact of donor type on outcome of bone marrow transplantation for Wiskott-Aldrich syndrome: collaborative study of the International Bone Marrow Transplant Registry and the National Marrow Donor Program.

Authors:  A H Filipovich; J V Stone; S C Tomany; M Ireland; C Kollman; C J Pelz; J T Casper; M J Cowan; J R Edwards; A Fasth; R P Gale; A Junker; N R Kamani; B J Loechelt; D W Pietryga; O Ringdén; M Vowels; J Hegland; A V Williams; J P Klein; K A Sobocinski; P A Rowlings; M M Horowitz
Journal:  Blood       Date:  2001-03-15       Impact factor: 22.113

2.  Autologous hematopoietic stem cell transplantation and conventional insulin therapy in the treatment of children with newly diagnosed type 1 diabetes: long term follow-up.

Authors:  Yi Gu; Chunxiu Gong; Xiaoxia Peng; Liya Wei; Chang Su; Miao Qin; Xi'ou Wang; Fengting Li
Journal:  Chin Med J (Engl)       Date:  2014       Impact factor: 2.628

3.  Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy.

Authors:  John M Lachin; Saul Genuth; Patricia Cleary; Matthew D Davis; David M Nathan
Journal:  N Engl J Med       Date:  2000-02-10       Impact factor: 91.245

4.  Comparative outcome of reduced intensity and myeloablative conditioning regimen in HLA identical sibling allogeneic haematopoietic stem cell transplantation for patients older than 50 years of age with acute myeloblastic leukaemia: a retrospective survey from the Acute Leukemia Working Party (ALWP) of the European group for Blood and Marrow Transplantation (EBMT).

Authors:  M Aoudjhane; M Labopin; N C Gorin; A Shimoni; T Ruutu; H-J Kolb; F Frassoni; J M Boiron; J L Yin; J Finke; H Shouten; D Blaise; M Falda; A A Fauser; J Esteve; E Polge; S Slavin; D Niederwieser; A Nagler; V Rocha
Journal:  Leukemia       Date:  2005-12       Impact factor: 11.528

5.  Reduced intensity haemopoietic stem-cell transplantation for treatment of non-malignant diseases in children.

Authors:  David A Jacobsohn; Reggie Duerst; William Tse; Morris Kletzel
Journal:  Lancet       Date:  2004 Jul 10-16       Impact factor: 79.321

6.  Estimating the cost of type 1 diabetes in the U.S.: a propensity score matching method.

Authors:  Betty Tao; Massimo Pietropaolo; Mark Atkinson; Desmond Schatz; David Taylor
Journal:  PLoS One       Date:  2010-07-09       Impact factor: 3.240

7.  Life table analysis of the risk of type 1 (insulin-dependent) diabetes mellitus in siblings according to islet cell antibodies and HLA markers. An 8-year prospective study.

Authors:  I Deschamps; C Boitard; J Hors; M Busson; A Marcelli-Barge; A Mogenet; J J Robert
Journal:  Diabetologia       Date:  1992-10       Impact factor: 10.122

8.  Autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus.

Authors:  Júlio C Voltarelli; Carlos E B Couri; Ana B P L Stracieri; Maria C Oliveira; Daniela A Moraes; Fabiano Pieroni; Marina Coutinho; Kelen C R Malmegrim; Maria C Foss-Freitas; Belinda P Simões; Milton C Foss; Elizabeth Squiers; Richard K Burt
Journal:  JAMA       Date:  2007-04-11       Impact factor: 56.272

Review 9.  Hematopoietic stem cell transplantation in childhood inherited bone marrow failure syndrome.

Authors:  E Gluckman; J E Wagner
Journal:  Bone Marrow Transplant       Date:  2007-12-17       Impact factor: 5.483

10.  HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: analysis of the type 1 diabetes genetics consortium families.

Authors:  Henry Erlich; Ana Maria Valdes; Janelle Noble; Joyce A Carlson; Mike Varney; Pat Concannon; Josyf C Mychaleckyj; John A Todd; Persia Bonella; Anna Lisa Fear; Eva Lavant; Anthony Louey; Priscilla Moonsamy
Journal:  Diabetes       Date:  2008-02-05       Impact factor: 9.461

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