Literature DB >> 27572084

Polymeric Quaternary Ammonium Compounds: Versatile Antimicrobial Materials.

Deanna L Zubris1, Kevin P C Minbiole, William M Wuest.   

Abstract

Polymeric Quaternary Ammonium Compounds (polyQACs) comprise a broad class of materials with applications in medical implants, food processing, and surface sanitizing, amongst many others. These polymeric substances are especially promising due to their potent antibacterial activity and limited hemolytic toxicity. In particular, many polyQACs have superior therapeutic indices and a lower likelihood of developing antibacterial resistance in comparison to their monomers, making them ideal materials for wound dressings, catheters, and other biomedical applications. This review outlines the history and development, previous successes, current state of the research, and future directions of polyQACs in society.

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Year:  2017        PMID: 27572084     DOI: 10.2174/1568026616666160829155805

Source DB:  PubMed          Journal:  Curr Top Med Chem        ISSN: 1568-0266            Impact factor:   3.295


  10 in total

Review 1.  Biological activity of quaternary ammonium salts and resistance of microorganisms to these compounds.

Authors:  Ewa Obłąk; Bożena Futoma-Kołoch; Anna Wieczyńska
Journal:  World J Microbiol Biotechnol       Date:  2021-01-11       Impact factor: 3.312

2.  Genomic Analysis of a Highly Virulent NDM-1-Producing Escherichia coli ST162 Infecting a Pygmy Sperm Whale (Kogia breviceps) in South America.

Authors:  Fábio P Sellera; Brenda Cardoso; Danny Fuentes-Castillo; Fernanda Esposito; Elder Sano; Herrison Fontana; Bruna Fuga; Daphne W Goldberg; Lourdes A V Seabra; Marzia Antonelli; Sandro Sandri; Cristiane K M Kolesnikovas; Nilton Lincopan
Journal:  Front Microbiol       Date:  2022-06-10       Impact factor: 6.064

3.  More QACs, more questions: Recent advances in structure activity relationships and hurdles in understanding resistance mechanisms.

Authors:  Kelly R Morrison; Ryan A Allen; Kevin P C Minbiole; William M Wuest
Journal:  Tetrahedron Lett       Date:  2019-07-26       Impact factor: 2.415

4.  An Investigation into Rigidity-Activity Relationships in BisQAC Amphiphilic Antiseptics.

Authors:  Renee C Kontos; Stephanie A Schallenhammer; Brian S Bentley; Kelly R Morrison; Javier A Feliciano; Julia A Tasca; Anna R Kaplan; Mark W Bezpalko; W Scott Kassel; William M Wuest; Kevin P C Minbiole
Journal:  ChemMedChem       Date:  2018-12-18       Impact factor: 3.466

5.  Decoupling the Functional Roles of Cationic and Hydrophobic Groups in the Antimicrobial and Hemolytic Activities of Methacrylate Random Copolymers.

Authors:  Hamid Mortazavian; Leanna L Foster; Rajani Bhat; Shyrie Patel; Kenichi Kuroda
Journal:  Biomacromolecules       Date:  2018-10-26       Impact factor: 6.988

6.  Broadening Activity of Polymyxin by Quaternary Ammonium Grafting.

Authors:  George M Ongwae; Kelly R Morrison; Ryan A Allen; Seonghoon Kim; Wonpil Im; William M Wuest; Marcos M Pires
Journal:  ACS Infect Dis       Date:  2020-04-03       Impact factor: 5.084

7.  Comparable Studies on Nanoscale Antibacterial Polymer Coatings Based on Different Coating Procedures.

Authors:  Thorsten Laube; Jürgen Weisser; Svea Sachse; Thomas Seemann; Ralf Wyrwa; Matthias Schnabelrauch
Journal:  Nanomaterials (Basel)       Date:  2022-02-11       Impact factor: 5.076

8.  Polymer Additives to Personal Protective Equipment can Inactivate Pathogens.

Authors:  Alan B Dogan; Katherine E Dabkowski; Jennifer L Cadnum; Curtis J Donskey; Horst A von Recum
Journal:  Ann Biomed Eng       Date:  2022-10-15       Impact factor: 4.219

Review 9.  Back to Basics: Choosing the Appropriate Surface Disinfectant.

Authors:  Angelica Artasensi; Sarah Mazzotta; Laura Fumagalli
Journal:  Antibiotics (Basel)       Date:  2021-05-21

Review 10.  Quaternary Ammonium Compounds (QACs) and Ionic Liquids (ILs) as Biocides: From Simple Antiseptics to Tunable Antimicrobials.

Authors:  Anatoly N Vereshchagin; Nikita A Frolov; Ksenia S Egorova; Marina M Seitkalieva; Valentine P Ananikov
Journal:  Int J Mol Sci       Date:  2021-06-24       Impact factor: 5.923

  10 in total

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