| Literature DB >> 27569199 |
Olga I Belykh1, Irina V Tikhonova2, Anton V Kuzmin2, Ekaterina G Sorokovikova2, Galina A Fedorova2, Igor V Khanaev2, Tatyana A Sherbakova2, Oleg A Timoshkin2.
Abstract
Cyanobacteria were screened from the surface of diseased sponges, stone and bedrock in Lake Baikal for the presence of saxitoxin using enzyme-linked immunosorbent assay. In sequel, eight paralytic shellfish toxin (PST) variants were identified using a MALDI mass spectrometry. Microscopic examination found that Tolypothrix distorta dominated in the biofouling samples. PCR and sequencing detected sxtA gene involved in saxitoxin biosynthesis, thereby providing evidence of the PST producing potential of Baikal cyanobacterial communities inhabiting different substrates.Entities:
Keywords: Benthic cyanobacteria; Lake Baikal; Paralytic shellfish toxins; Saxitoxin; Sponge disease; Tolypothrix distorta
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Year: 2016 PMID： 27569199 DOI： 10.1016/j.toxicon.2016.08.015
Source DB: PubMed Journal: Toxicon ISSN： 0041-0101 Impact factor: 3.033