Literature DB >> 27568513

Loss of treatment benefit when heroin-assisted treatment is stopped after 12 months.

Isabelle Demaret1, Etienne Quertemont2, Géraldine Litran3, Cécile Magoga3, Clémence Deblire3, Nathalie Dubois4, Corinne Charlier4, André Lemaitre5, Marc Ansseau6.   

Abstract

PURPOSE: In 2013, during a recent heroin-assisted treatment trial, participants in heroin-assisted treatment (HAT) decreased significantly more their street heroin use than participants in oral methadone treatment. After the trial, HAT was discontinued. To examine whether the treatment benefits were sustained three months after the trial, the use of street heroin by the participants was analyzed in a follow-up study.
RESULTS: At the follow-up assessment, street heroin use increased in the experimental group. The two groups no longer showed a significant difference (p=0.55) in the level of street heroin use.
CONCLUSION: A predetermined and forced end of HAT was followed by a significant increase in the level of street level use.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Diacetylmorphine; Heroin-assisted treatment; Substitution treatment; Treatment duration

Mesh:

Substances:

Year:  2016        PMID: 27568513     DOI: 10.1016/j.jsat.2016.06.005

Source DB:  PubMed          Journal:  J Subst Abuse Treat        ISSN: 0740-5472


  2 in total

Review 1.  Supervised Injectable Opioid Treatment for the Management of Opioid Dependence.

Authors:  James Bell; Vendula Belackova; Nicholas Lintzeris
Journal:  Drugs       Date:  2018-09       Impact factor: 9.546

2.  Injectable opioid agonist treatment for opioid use disorder: a national clinical guideline.

Authors:  Nadia Fairbairn; Josey Ross; Michael Trew; Karine Meador; Jeff Turnbull; Scott MacDonald; Eugenia Oviedo-Joekes; Bernard Le Foll; Marie-Ève Goyer; Michel Perreault; Christy Sutherland
Journal:  CMAJ       Date:  2019-09-23       Impact factor: 8.262

  2 in total

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