Mohammad W Godah1, Rima A Abdul Khalek2, Lama Kilzar3, Hiba Zeid4, Acile Nahlawi3, Luciane Cruz Lopes5, Andrea J Darzi2, Holger J Schünemann6, Elie A Akl7. 1. Clinical Research Institute, American University of Beirut, Beirut, Lebanon; Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon; AUB GRADE Center, Clinical Research Institute, American University of Beirut, Beirut, Lebanon. 2. Clinical Research Institute, American University of Beirut, Beirut, Lebanon; AUB GRADE Center, Clinical Research Institute, American University of Beirut, Beirut, Lebanon. 3. Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon. 4. Clinical Research Institute, American University of Beirut, Beirut, Lebanon. 5. Pharmaceutical Sciences, University of Sorocaba, UNISO, Sorocaba, São Paulo, Brazil. 6. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; McMaster GRADE Center and Department of Medicine, McMaster University, Hamilton, Ontario, Canada. 7. Clinical Research Institute, American University of Beirut, Beirut, Lebanon; Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon; AUB GRADE Center, Clinical Research Institute, American University of Beirut, Beirut, Lebanon; Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Department of Medicine, American University of Beirut, Beirut, Lebanon. Electronic address: ea32@aub.edu.lb.
Abstract
BACKGROUND: Low- and middle-income countries adapt World Health Organization (WHO) guidelines instead of de novo development for financial, epidemiologic, sociopolitical, cultural, organizational, and other reasons. OBJECTIVE: To systematically evaluate reported processes used in the adaptation of WHO guidelines for human immunodeficiency virus (HIV) and tuberculosis (TB). METHODS: We searched three online databases/repositories: United States Agency for International Development (USAID) AIDS Support and Technical Resources - Sector One program (AIDSTAR-One) National Treatment Database; the AIDSspace Guideline Repository, and WHO Database of national HIV and TB guidelines. We assessed the rigor and quality of reported adaptation methodology using the ADAPTE process as benchmark. RESULTS: Of 170 eligible guidelines, only 32 (19%) reported documentation on the adaptation process. The median and interquartile range of the number of ADAPTE steps fulfilled by the eligible guidelines were 11.5 (10, 13.5) (out of 23 steps). The number of guidelines (out of 32 steps) fulfilling each ADAPTE step was 18 (interquartile range, 5-27). Seventeen of 32 guidelines (53%) met all steps relevant to the setup phase, whereas none met all steps relevant to the adaptation phase. CONCLUSION: The number of well-documented adaptation methodologies in national HIV and/or TB guidelines is very low. There is a need for the use of standardized and systematic framework for guideline adaptation and improved reporting of processes used.
BACKGROUND: Low- and middle-income countries adapt World Health Organization (WHO) guidelines instead of de novo development for financial, epidemiologic, sociopolitical, cultural, organizational, and other reasons. OBJECTIVE: To systematically evaluate reported processes used in the adaptation of WHO guidelines for human immunodeficiency virus (HIV) and tuberculosis (TB). METHODS: We searched three online databases/repositories: United States Agency for International Development (USAID) AIDS Support and Technical Resources - Sector One program (AIDSTAR-One) National Treatment Database; the AIDSspace Guideline Repository, and WHO Database of national HIV and TB guidelines. We assessed the rigor and quality of reported adaptation methodology using the ADAPTE process as benchmark. RESULTS: Of 170 eligible guidelines, only 32 (19%) reported documentation on the adaptation process. The median and interquartile range of the number of ADAPTE steps fulfilled by the eligible guidelines were 11.5 (10, 13.5) (out of 23 steps). The number of guidelines (out of 32 steps) fulfilling each ADAPTE step was 18 (interquartile range, 5-27). Seventeen of 32 guidelines (53%) met all steps relevant to the setup phase, whereas none met all steps relevant to the adaptation phase. CONCLUSION: The number of well-documented adaptation methodologies in national HIV and/or TB guidelines is very low. There is a need for the use of standardized and systematic framework for guideline adaptation and improved reporting of processes used.
Authors: Rima A Abdul-Khalek; Andrea J Darzi; Mohammad W Godah; Lama Kilzar; Chantal Lakis; Arnav Agarwal; Elias Abou-Jaoude; Joerg J Meerpohl; Wojtek Wiercioch; Nancy Santesso; Hneine Brax; Holger Schünemann; Elie A Akl Journal: J Glob Health Date: 2017-12 Impact factor: 4.413
Authors: Yang Song; Andrea Darzi; Monica Ballesteros; Laura Martínez García; Pablo Alonso-Coello; Thurayya Arayssi; Soumyadeep Bhaumik; Yaolong Chen; Francoise Cluzeau; Davina Ghersi; Paulina F Padilla; Etienne V Langlois; Holger J Schünemann; Robin W M Vernooij; Elie A Akl Journal: BMJ Open Date: 2019-09-24 Impact factor: 2.692
Authors: Lara A Kahale; Hella Ouertatani; Asma Ben Brahem; Hela Grati; Mohammed Ben Hamouda; Zuleika Saz-Parkinson; Elie A Akl Journal: Health Res Policy Syst Date: 2021-05-13
Authors: Yang Song; Monica Ballesteros; Jing Li; Laura Martínez García; Ena Niño de Guzmán; Robin W M Vernooij; Elie A Akl; Francoise Cluzeau; Pablo Alonso-Coello Journal: BMJ Open Date: 2021-12-02 Impact factor: 2.692