Literature DB >> 27563009

NEK7: a novel promising therapy target for NLRP3-related inflammatory diseases.

Jin Xu1, Liqun Lu1, Lanfang Li2.   

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Year:  2016        PMID： 27563009     DOI： 10.1093/abbs/gmw080

Source DB:  PubMed          Journal:  Acta Biochim Biophys Sin (Shanghai)        ISSN： 1672-9145            Impact factor:   3.848


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  11 in total

Review 1.  In depth analysis of kinase cross screening data to identify chemical starting points for inhibition of the Nek family of kinases.

Authors:  C I Wells; N R Kapadia; R M Couñago; D H Drewry
Journal:  Medchemcomm       Date:  2017-12-08       Impact factor: 3.597

2.  Deep Learning and Structure-Based Virtual Screening for Drug Discovery against NEK7: A Novel Target for the Treatment of Cancer.

Authors:  Mubashir Aziz; Syeda Abida Ejaz; Seema Zargar; Naveed Akhtar; Abdullahi Tunde Aborode; Tanveer A Wani; Gaber El-Saber Batiha; Farhan Siddique; Mohammed Alqarni; Ashraf Akintayo Akintola
Journal:  Molecules       Date:  2022-06-25       Impact factor: 4.927

Review 3.  Update of inflammasome activation in microglia/macrophage in aging and aging-related disease.

Authors:  Meng-Yan Hu; Yin-Yao Lin; Bing-Jun Zhang; Dan-Li Lu; Zheng-Qi Lu; Wei Cai
Journal:  CNS Neurosci Ther       Date:  2019-11-14       Impact factor: 5.243

Review 4.  NLRP3 Inflammasome and Its Critical Role in Gynecological Disorders and Obstetrical Complications.

Authors:  Xuhui Fang; Yanshi Wang; Yu Zhang; Yelin Li; Joanne Kwak-Kim; Li Wu
Journal:  Front Immunol       Date:  2021-01-28       Impact factor: 7.561

Review 5.  Physiological and Pathological Roles of Mammalian NEK7.

Authors:  Zhenzhen Sun; Wei Gong; Yue Zhang; Zhanjun Jia
Journal:  Front Physiol       Date:  2020-12-07       Impact factor: 4.566

6.  PKA and Epac1 Reduce Nek7 to Block the NLRP3 Inflammasome Proteins in the Retinal Vasculature.

Authors:  Li Liu; Youde Jiang; Jena J Steinle
Journal:  Invest Ophthalmol Vis Sci       Date:  2022-01-03       Impact factor: 4.799

7.  BMP-7 Attenuates Inflammation-Induced Pyroptosis and Improves Cardiac Repair in Diabetic Cardiomyopathy.

Authors:  Ibrahim Elmadbouh; Dinender K Singla
Journal:  Cells       Date:  2021-10-02       Impact factor: 6.600

8.  Inhibition of NEK7 Suppressed Hepatocellular Carcinoma Progression by Mediating Cancer Cell Pyroptosis.

Authors:  Zilong Yan; Qingen Da; Zhangfu Li; Qirui Lin; Jing Yi; Yanze Su; Guanyin Yu; Qingqi Ren; Xu Liu; Zewei Lin; Jianhua Qu; Weihua Yin; Jikui Liu
Journal:  Front Oncol       Date:  2022-02-10       Impact factor: 6.244

9.  FMDV Leader Protein Interacts with the NACHT and LRR Domains of NLRP3 to Promote IL-1β Production.

Authors:  Sk Mohiuddin Choudhury; Xusheng Ma; Yuanyuan Li; Xiaofeng Nian; Zhikuan Luo; Yonghua Ma; Zixiang Zhu; Fan Yang; Weijun Cao; Haixue Zheng
Journal:  Viruses       Date:  2021-12-23       Impact factor: 5.048

Review 10.  Current Advances in Coptidis Rhizoma for Gastrointestinal and Other Cancers.

Authors:  Luying He; Zhangfeng Zhong; Man Chen; Qilian Liang; Yitao Wang; Wen Tan
Journal:  Front Pharmacol       Date:  2022-01-03       Impact factor: 5.988
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