| Literature DB >> 27561220 |
Jorge Alfonso Martín-Trejo1, Juan Carlos Núñez-Enríquez2, Arturo Fajardo-Gutiérrez2, Aurora Medina-Sansón3, Janet Flores-Lujano2, Elva Jiménez-Hernández4, Raquel Amador-Sanchez5, José Gabriel Peñaloza-Gonzalez6, Francisco Javier Alvarez-Rodriguez7, Victoria Bolea-Murga8, Rosa Martha Espinosa-Elizondo8, José de Diego Flores-Chapa9, Maria Luisa Pérez-Saldivar2, María Del Carmen Rodriguez-Zepeda1, Elisa María Dorantes-Acosta3, Nora Nancy Núñez-Villegas4, Martha Margarita Velazquez-Aviña6, José Refugio Torres-Nava7, Nancy Carolina Reyes-Zepeda9, César Raúl González-Bonilla10, Luz Victoria Flores-Villegas9, Angélica Rangel-López2,11, Roberto Rivera-Luna12, Rogelio Paredes-Aguilera13, Rocío Cárdenas-Cardós14, Armando Martínez-Avalos14, Ana Elena Gil-Hernández2, David Aldebarán Duarte-Rodríguez2, Juan Manuel Mejía-Aranguré2,11.
Abstract
The role of malnutrition at diagnosis as a predictor of early mortality in Mexican leukemia children remains controversial. The objective of present study was to investigate whether malnutrition was a predictor of early mortality during the first year of treatment in Mexican acute lymphoblastic leukemia (ALL) children through the first population-based study. A total of 794 newly diagnosed ALL pediatric patients from public hospitals of Mexico City were enrolled. A multivariate Cox proportional hazards regression model was constructed and adjusted by patient's age at diagnosis, gender, hospital of treatment, and socioeconomic status. Early mortality was high (12.1%) and malnutrition by different indicators was not associated with mortality at induction phase and at 6th month; a high risk of dying (RR = 2.08; 95% CI: 1.08-4.01) was observed in the group of malnourished children with a high-risk ALL.Entities:
Keywords: Leukemia; children; malnutrition; mortality; prognosis
Mesh：
Year: 2016 PMID： 27561220 DOI： 10.1080/10428194.2016.1219904
Source DB: PubMed Journal: Leuk Lymphoma ISSN： 1026-8022