| Literature DB >> 27560204 |
Midori Nagamoto1, Tomoyuki Yanagi1, Takahiro Nishimura1, Hideki Yorimitsu1.
Abstract
Iridium/chiral diene complexes efficiently catalyzed the asymmetric cyclization of N-sulfonyl alkenyl amides to give the corresponding 2-pyrrolidone derivatives with high enantioselectivity. A mechanistic study revealed that the reaction proceeds via nucleophilic attack of the amide on the alkene moiety.Entities:
Year: 2016 PMID： 27560204 DOI： 10.1021/acs.orglett.6b01954
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005