Literature DB >> 27559620

Disabled-2; an autophagic and apoptotic switch.

Yong Jiang1, Alec N Woosley1, Philip H Howe1,2.   

Abstract

Keywords:  Apoptosis; Cathepsin B; Disabled-2; TGFb; autophagy

Mesh:

Year:  2016        PMID: 27559620      PMCID: PMC5224445          DOI: 10.1080/15384101.2016.1222747

Source DB:  PubMed          Journal:  Cell Cycle        ISSN: 1551-4005            Impact factor:   4.534


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  7 in total

1.  Cathepsin-B-mediated cleavage of Disabled-2 regulates TGF-β-induced autophagy.

Authors:  Yong Jiang; Alec N Woosley; Nageswaran Sivalingam; Sneha Natarajan; Philip H Howe
Journal:  Nat Cell Biol       Date:  2016-07-11       Impact factor: 28.824

Review 2.  A perspective on cancer cell metastasis.

Authors:  Christine L Chaffer; Robert A Weinberg
Journal:  Science       Date:  2011-03-25       Impact factor: 47.728

3.  Epigenetic downregulation of human disabled homolog 2 switches TGF-beta from a tumor suppressor to a tumor promoter.

Authors:  Adèle Hannigan; Paul Smith; Gabriela Kalna; Cristiana Lo Nigro; Clare Orange; Darren I O'Brien; Reshma Shah; Nelofer Syed; Lindsay C Spender; Blanca Herrera; Johanna K Thurlow; Laura Lattanzio; Martino Monteverde; Meghan E Maurer; Francesca M Buffa; Jelena Mann; David C K Chu; Catharine M L West; Max Patridge; Karin A Oien; Jonathan A Cooper; Margaret C Frame; Adrian L Harris; Louise Hiller; Linda J Nicholson; Milena Gasco; Tim Crook; Gareth J Inman
Journal:  J Clin Invest       Date:  2010-07-01       Impact factor: 14.808

4.  TGF-beta-mediated phosphorylation of hnRNP E1 induces EMT via transcript-selective translational induction of Dab2 and ILEI.

Authors:  Arindam Chaudhury; George S Hussey; Partho S Ray; Ge Jin; Paul L Fox; Philip H Howe
Journal:  Nat Cell Biol       Date:  2010-02-14       Impact factor: 28.824

5.  The inhibitory effects of Disabled-2 (Dab2) on Wnt signaling are mediated through Axin.

Authors:  Y Jiang; C Prunier; P H Howe
Journal:  Oncogene       Date:  2007-10-08       Impact factor: 9.867

6.  DOC-2/hDab2, a candidate tumor suppressor gene involved in the development of gestational trophoblastic diseases.

Authors:  V Fulop; C V Colitti; D Genest; R S Berkowitz; G K Yiu; S W Ng; J Szepesi; S C Mok
Journal:  Oncogene       Date:  1998-07-30       Impact factor: 9.867

Review 7.  Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment.

Authors:  X Sui; R Chen; Z Wang; Z Huang; N Kong; M Zhang; W Han; F Lou; J Yang; Q Zhang; X Wang; C He; H Pan
Journal:  Cell Death Dis       Date:  2013-10-10       Impact factor: 8.469

  7 in total
  1 in total

Review 1.  Emerging Roles of Disabled Homolog 2 (DAB2) in Immune Regulation.

Authors:  Vanessa Figliuolo da Paz; Fayez K Ghishan; Pawel R Kiela
Journal:  Front Immunol       Date:  2020-10-15       Impact factor: 7.561

  1 in total

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