Literature DB >> 27558601

Derivation of the clinical grade human embryonic stem cell line RCe013-A (RC-9).

P A De Sousa1, B J Tye2, K Bruce2, P Dand2, G Russell2, D M Collins2, A Greenshields2, K McDonald2, H Bradburn2, M A Canham3, T Kunath3, J M Downie2, M Bateman2, A Courtney2.   

Abstract

The human embryonic stem cell line RCe013-A (RC-9) was derived under quality assured compliance with UK regulation, European Union Directives and International guidance for tissue procurement, processing and storage according to Good Manufacturing Practice (GMP) standards. The cell line was derived from a failed to fertilise oocyte voluntarily donated as unsuitable and surplus to fertility requirements following informed consent. RCe013-A (RC-9) shows normal pluripotency marker expression and differentiation to the three germ layers in vitro and in vivo. It has a normal 46XY male karyotype and microsatellite PCR identity, HLA and blood group typing data are available.
Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

Entities:  

Year:  2016        PMID: 27558601     DOI: 10.1016/j.scr.2016.04.020

Source DB:  PubMed          Journal:  Stem Cell Res        ISSN: 1873-5061            Impact factor:   2.020


  5 in total

1.  High quality clinical grade human embryonic stem cell lines derived from fresh discarded embryos.

Authors:  Jinpei Ye; Nicola Bates; Despina Soteriou; Lisa Grady; Clare Edmond; Alex Ross; Alan Kerby; Philip A Lewis; Tope Adeniyi; Ronnie Wright; Kay V Poulton; Marcus Lowe; Susan J Kimber; Daniel R Brison
Journal:  Stem Cell Res Ther       Date:  2017-06-05       Impact factor: 6.832

2.  Vimentin expression is retained in erythroid cells differentiated from human iPSC and ESC and indicates dysregulation in these cells early in differentiation.

Authors:  Kongtana Trakarnsanga; Daniel Ferguson; Deborah E Daniels; Rebecca E Griffiths; Marieangela C Wilson; Kathryn E Mordue; Abi Gartner; Tatyana N Andrienko; Annabel Calvert; Alison Condie; Angela McCahill; Joanne C Mountford; Ashley M Toye; David J Anstee; Jan Frayne
Journal:  Stem Cell Res Ther       Date:  2019-04-29       Impact factor: 6.832

3.  Automation of human pluripotent stem cell differentiation toward retinal pigment epithelial cells for large-scale productions.

Authors:  Florian Regent; Lise Morizur; Léa Lesueur; Walter Habeler; Alexandra Plancheron; Karim Ben M'Barek; Christelle Monville
Journal:  Sci Rep       Date:  2019-07-23       Impact factor: 4.379

4.  Semi-3D cultures using Laminin 221 as a coating material for human induced pluripotent stem cells.

Authors:  Yoshiki Nakashima; Shinsuke Yoshida; Masayoshi Tsukahara
Journal:  Regen Biomater       Date:  2022-09-05

Review 5.  Clinical-Grade Human Pluripotent Stem Cells for Cell Therapy: Characterization Strategy.

Authors:  Daniela Rehakova; Tereza Souralova; Irena Koutna
Journal:  Int J Mol Sci       Date:  2020-03-31       Impact factor: 5.923

  5 in total

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