Literature DB >> 27556758

The Role of Pressure Offloading on Diabetic Foot Ulcer Healing and Prevention of Recurrence.

Sicco A Bus1.   

Abstract

BACKGROUND: An increased plantar pressure is a causative factor in the development of plantar foot ulcers in people with diabetes mellitus, and ulcers are a precursor of lower extremity amputation.
METHODS: In this article, the evidence is reviewed that relieving areas of increased plantar pressure (ie, offloading) can heal plantar foot ulcers and prevent their recurrence.
RESULTS: Noninfected, nonischemic neuropathic plantar forefoot ulcers should heal in 6 to 8 weeks with adequate offloading. Recent meta-analyses and systematic reviews show that nonremovable knee-high devices are most effective. This is probably because they eliminate the problem of nonadherence with the use of a removable device. Studies show a large discrepancy between evidence-based recommendations on offloading and what is used in clinical practice. Many clinics continue to use methods that are less effective or have not been proven to be effective, while ignoring evidence-based methods. Strategies are proposed to address this issue, notably the adoption and implementation of recent international guidelines by professional societies and a stronger focus of clinicians on expedited healing. For the prevention of plantar foot ulcer recurrence in high-risk patients, 2 recent trials have shown that the incidence of recurrence can be significantly reduced with custom-made footwear that has a demonstrated pressure-relieving effect through guidance by plantar pressure measurements, under the condition that the footwear is worn.
CONCLUSION: This review helps to inform clinicians about effective offloading treatment for healing plantar foot ulcers and preventing their recurrence.

Entities:  

Mesh:

Year:  2016        PMID: 27556758     DOI: 10.1097/PRS.0000000000002686

Source DB:  PubMed          Journal:  Plast Reconstr Surg        ISSN: 0032-1052            Impact factor:   4.730


  13 in total

1.  [Interpretation of 2019 International Working Group on Diabetic Foot guidelines on the prevention and management of diabetic foot disease].

Authors:  Lei Gao; Jiangning Wang; Yefeng Yin
Journal:  Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi       Date:  2020-01-15

2.  Measuring Plantar Tissue Stress in People With Diabetic Peripheral Neuropathy: A Critical Concept in Diabetic Foot Management.

Authors:  Peter A Lazzarini; Ryan T Crews; Jaap J van Netten; Sicco A Bus; Malindu E Fernando; Paul J Chadwick; Bijan Najafi
Journal:  J Diabetes Sci Technol       Date:  2019-04-29

3.  Decreasing an Offloading Device's Size and Offsetting Its Imposed Limb-Length Discrepancy Lead to Improved Comfort and Gait.

Authors:  Ryan T Crews; Joseph Candela
Journal:  Diabetes Care       Date:  2018-04-17       Impact factor: 19.112

Review 4.  Update on management of diabetic foot ulcers.

Authors:  Estelle Everett; Nestoras Mathioudakis
Journal:  Ann N Y Acad Sci       Date:  2018-01       Impact factor: 5.691

5.  The efficacy of removable devices to offload and heal neuropathic plantar forefoot ulcers in people with diabetes: a single-blinded multicentre randomised controlled trial.

Authors:  Sicco A Bus; Jaap J van Netten; Anke Ir Kottink; Erik A Manning; Maximilian Spraul; Arend-Jan Woittiez; Jeff G van Baal
Journal:  Int Wound J       Date:  2017-10-23       Impact factor: 3.315

6.  Evaluation of the use of therapeutic footwear in people with diabetes mellitus - a scoping review.

Authors:  Juliana Vallim Jorgetto; Mônica Antar Gamba; Denise Miyuki Kusahara
Journal:  J Diabetes Metab Disord       Date:  2019-08-14

7.  Surgical OFF-LOADING of the diabetic foot.

Authors:  Luca Dalla Paola; Anna Carone; Marialuisa Valente; Mariano Palena; Giuseppe Scavone
Journal:  J Clin Orthop Trauma       Date:  2021-01-22

8.  Surgical offloading procedures for diabetic foot ulcers compared to best non-surgical treatment: a study protocol for a randomized controlled trial.

Authors:  Aharon S Finestone; Eran Tamir; Guy Ron; Itay Wiser; Gabriel Agar
Journal:  J Foot Ankle Res       Date:  2018-02-20       Impact factor: 2.303

9.  Plantar pressure changes in hindfoot relief devices of different designs.

Authors:  F Mazur; B Swoboda; H D Carl; C Lutter; M Engelhardt; M W Hoppe; T Hotfiel; C Grim
Journal:  J Exp Orthop       Date:  2019-02-07

10.  A novel dressing seeded with embryonic artery CD133+ cells and loaded with the Sirt1 agonist SRT1720 accelerates the healing of diabetic ischemic ulcers.

Authors:  Pan-Ke Cheng; Xiao-Long Chen; Xing-Xing Su; Xue-Jiao Su; Chun-Li Hou
Journal:  Exp Ther Med       Date:  2018-04-25       Impact factor: 2.447

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