Literature DB >> 27555703

Calculating incidence and prognosis in a prospective study.

Kanica Kaushal1.   

Abstract

Entities:  

Year:  2016        PMID: 27555703      PMCID: PMC4968071          DOI: 10.4103/0972-5229.186267

Source DB:  PubMed          Journal:  Indian J Crit Care Med        ISSN: 0972-5229


× No keyword cloud information.
Sir, This is in reference to the article, “Acute kidney injury (AKI)-incidence, prognostic factors, and outcome of patients in an Intensive Care Unit in a tertiary center: A prospective observational study.”[1] The authors have done a commendable job to find the incidence, prognostic factors, and outcome of patients with AKI. However, I have a few concerns regarding the type of study and methodology being adopted in the present study. First, the authors have written in their material and methods that the study done was a prospective, observational, and cross-sectional study conducted in the hospital. The epidemiologic studies are either descriptive or analytical studies. Descriptive studies include case reports, case series reports, cross-sectional studies, surveillance studies, and ecological studies, whereas analytical studies are either experimental or observational. A prospective study is a type of observational study.[2] Hence, how can a study be “cross-sectional, that is descriptive” and “prospective” at the same time? The aim of this study is to analyze the incidence, prognostic factors, and 28 days outcome of AKI. Hence, this is a “prospective cohort” study. The cross-sectional study tells about the characteristics of a population at one point in time (like a photo “snapshot”) and is used to estimate the prevalence (not incidence) of a health condition or prevalence of a behavior, risk factor, or potential for disease.[2] Further, the authors have provided the incidence of AKI in critically ill patients during the study period of 6 months as 16.1% (as a percentage), whereas incidence being a rate, should have been quoted just as 16.1/1000 Intensive Care Unit admissions and not as a percentage. Incidence rate refers during a given time period in a specified population at risk. The measure most often used is person years and not percentage.[3] Finally, prognosis can be expressed either in term of deaths from the disease or in terms of survivors with the disease. In describing survival after diagnosis of AKI, it must have been more useful to present incidence data in a plot of cumulative incidence over time, taking into account loss to follow-up, using a Kaplan-Meier plot.[4]

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.
  2 in total

1.  Prospective cohort versus retrospective cohort studies to estimate incidence.

Authors:  Kanica Kaushal
Journal:  Indian J Crit Care Med       Date:  2014-12

2.  Acute kidney injury-incidence, prognostic factors, and outcome of patients in an Intensive Care Unit in a tertiary center: A prospective observational study.

Authors:  Sara Korula; Sindhu Balakrishnan; Shyam Sundar; Vergis Paul; Anuroop Balagopal
Journal:  Indian J Crit Care Med       Date:  2016-06
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.