Literature DB >> 27555346

Somatic Genome Editing Goes Viral.

Maria Paz Zafra1, Lukas E Dow2.   

Abstract

Generating new mouse models of cancer is a challenging and laborious task that can require years of investment to interrogate a single gene. Now, Jonkers and colleagues describe the first application of CRISPR-based genome editing in the mammary gland, providing a new approach to dissect complex genetic interactions in vivo. Published by Elsevier Ltd.

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Year:  2016        PMID： 27555346      PMCID： PMC5048560          DOI： 10.1016/j.molmed.2016.08.004

Source DB:  PubMed          Journal:  Trends Mol Med        ISSN： 1471-4914            Impact factor:   11.951


  10 in total

1.  CRISPR-Cas9 knockin mice for genome editing and cancer modeling.

Authors:  Randall J Platt; Sidi Chen; Yang Zhou; Michael J Yim; Lukasz Swiech; Hannah R Kempton; James E Dahlman; Oren Parnas; Thomas M Eisenhaure; Marko Jovanovic; Daniel B Graham; Siddharth Jhunjhunwala; Matthias Heidenreich; Ramnik J Xavier; Robert Langer; Daniel G Anderson; Nir Hacohen; Aviv Regev; Guoping Feng; Phillip A Sharp; Feng Zhang
Journal:  Cell       Date:  2014-09-25       Impact factor: 41.582

2.  Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses.

Authors:  Dan Wang; Haiwei Mou; Shaoyong Li; Yingxiang Li; Soren Hough; Karen Tran; Jia Li; Hao Yin; Daniel G Anderson; Erik J Sontheimer; Zhiping Weng; Guangping Gao; Wen Xue
Journal:  Hum Gene Ther       Date:  2015-07       Impact factor: 5.695

3.  In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9.

Authors:  Lukasz Swiech; Matthias Heidenreich; Abhishek Banerjee; Naomi Habib; Yinqing Li; John Trombetta; Mriganka Sur; Feng Zhang
Journal:  Nat Biotechnol       Date:  2014-10-19       Impact factor: 54.908

4.  Simple and rapid in vivo generation of chromosomal rearrangements using CRISPR/Cas9 technology.

Authors:  Rafael B Blasco; Elif Karaca; Chiara Ambrogio; Taek-Chin Cheong; Emre Karayol; Valerio G Minero; Claudia Voena; Roberto Chiarle
Journal:  Cell Rep       Date:  2014-11-13       Impact factor: 9.423

5.  In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system.

Authors:  Danilo Maddalo; Eusebio Manchado; Carla P Concepcion; Ciro Bonetti; Joana A Vidigal; Yoon-Chi Han; Paul Ogrodowski; Alessandra Crippa; Natasha Rekhtman; Elisa de Stanchina; Scott W Lowe; Andrea Ventura
Journal:  Nature       Date:  2014-10-22       Impact factor: 49.962

6.  Inducible in vivo genome editing with CRISPR-Cas9.

Authors:  Lukas E Dow; Jonathan Fisher; Kevin P O'Rourke; Ashlesha Muley; Edward R Kastenhuber; Geulah Livshits; Darjus F Tschaharganeh; Nicholas D Socci; Scott W Lowe
Journal:  Nat Biotechnol       Date:  2015-02-18       Impact factor: 54.908

7.  Rapid modelling of cooperating genetic events in cancer through somatic genome editing.

Authors:  Francisco J Sánchez-Rivera; Thales Papagiannakopoulos; Rodrigo Romero; Tuomas Tammela; Matthew R Bauer; Arjun Bhutkar; Nikhil S Joshi; Lakshmipriya Subbaraj; Roderick T Bronson; Wen Xue; Tyler Jacks
Journal:  Nature       Date:  2014-10-22       Impact factor: 49.962

8.  CRISPR-mediated direct mutation of cancer genes in the mouse liver.

Authors:  Wen Xue; Sidi Chen; Hao Yin; Tuomas Tammela; Thales Papagiannakopoulos; Nikhil S Joshi; Wenxin Cai; Gillian Yang; Roderick Bronson; Denise G Crowley; Feng Zhang; Daniel G Anderson; Phillip A Sharp; Tyler Jacks
Journal:  Nature       Date:  2014-08-06       Impact factor: 49.962

9.  Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice.

Authors:  Roman Maresch; Sebastian Mueller; Christian Veltkamp; Rupert Öllinger; Mathias Friedrich; Irina Heid; Katja Steiger; Julia Weber; Thomas Engleitner; Maxim Barenboim; Sabine Klein; Sandra Louzada; Ruby Banerjee; Alexander Strong; Teresa Stauber; Nina Gross; Ulf Geumann; Sebastian Lange; Marc Ringelhan; Ignacio Varela; Kristian Unger; Fengtang Yang; Roland M Schmid; George S Vassiliou; Rickmer Braren; Günter Schneider; Mathias Heikenwalder; Allan Bradley; Dieter Saur; Roland Rad
Journal:  Nat Commun       Date:  2016-02-26       Impact factor: 14.919

10.  Modeling invasive lobular breast carcinoma by CRISPR/Cas9-mediated somatic genome editing of the mammary gland.

Authors:  Stefano Annunziato; Sjors M Kas; Micha Nethe; Hatice Yücel; Jessica Del Bravo; Colin Pritchard; Rahmen Bin Ali; Bas van Gerwen; Bjørn Siteur; Anne Paulien Drenth; Eva Schut; Marieke van de Ven; Mirjam C Boelens; Sjoerd Klarenbeek; Ivo J Huijbers; Martine H van Miltenburg; Jos Jonkers
Journal:  Genes Dev       Date:  2016-06-15       Impact factor: 11.361
  10 in total

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