Literature DB >> 27554811

Acute asthma, prognosis, and treatment.

Jennifer E Fergeson1, Shiven S Patel2, Richard F Lockey2.   

Abstract

Asthma affects about 300 million people globally and accounts for 1 in every 250 deaths in the world. Approximately 12 million people in the United States each year experience an acute exacerbation of their asthma, a quarter of which require hospitalization. Acute asthma should be differentiated from poor asthma control. Patients with acute asthma will exhibit increasing shortness of breath, chest tightness, coughing, and/or wheezing. In contrast, poor asthma control typically presents with a diurnal variability in airflow and is a characteristic that is usually not seen during an acute exacerbation. The history should include a review of comorbidities, adherence to medications, previous episodes of near-fatal asthma, and whether the patient has experienced multiple emergency department visits or hospitalizations, particularly those requiring admission to an intensive care unit involving respiratory failure, intubation, and mechanical ventilation. Patient education is important to ensure that the patient understands that asthma is mostly a chronic disease and necessitates the avoidance of allergens, prevention of infections, adherence with routine vaccinations, management of comorbid conditions, and adherence to treatment regimens. This article is a structured review of the available literature regarding the diagnosis and management of acute asthma.
Copyright © 2016. Published by Elsevier Inc.

Entities:  

Keywords:  Asthma flare; acute asthma; acute asthma diagnosis; acute asthma management; asthma attack; wheezing

Mesh:

Substances:

Year:  2016        PMID: 27554811     DOI: 10.1016/j.jaci.2016.06.054

Source DB:  PubMed          Journal:  J Allergy Clin Immunol        ISSN: 0091-6749            Impact factor:   10.793


  28 in total

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Authors:  Sannette C Hall; Devendra K Agrawal
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Authors:  Amira Ali Ramadan; Jonathan M Gaffin; Elliot Israel; Wanda Phipatanakul
Journal:  Clin Chest Med       Date:  2019-03       Impact factor: 2.878

3.  Asthma and Post-Asthmatic Fibrosis: A Search for New Promising Molecular Markers of Transition from Acute Inflammation to Pulmonary Fibrosis.

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Journal:  Biomedicines       Date:  2022-04-28

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Authors:  Hua Yan; Guiying Qian; Rui Yang; Zichen Luo; Xianzheng Wang; Tong Xie; Xia Zhao; Jinjun Shan
Journal:  Front Pharmacol       Date:  2021-04-23       Impact factor: 5.810

5.  Cyclophilin A Plays Potential Roles in a Rat Model of Asthma and Suppression of Immune Response.

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Journal:  J Asthma Allergy       Date:  2021-05-07

6.  Continuous versus intermittent short-acting β2-agonists nebulization as first-line therapy in hospitalized children with severe asthma exacerbation: a propensity score matching analysis.

Authors:  Prapasri Kulalert; Phichayut Phinyo; Jayanton Patumanond; Chutima Smathakanee; Wantida Chuenjit; Sira Nanthapisal
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7.  Schisandrin B Attenuates Airway Inflammation and Airway Remodeling in Asthma by Inhibiting NLRP3 Inflammasome Activation and Reducing Pyroptosis.

Authors:  Xiufeng Chen; Zhen Xiao; Zhiyan Jiang; Yonghong Jiang; Wen Li; Mingjing Wang
Journal:  Inflammation       Date:  2021-06-18       Impact factor: 4.092

8.  Bergenin, a PPARγ agonist, inhibits Th17 differentiation and subsequent neutrophilic asthma by preventing GLS1-dependent glutaminolysis.

Authors:  Ling Yang; Yun Zheng; Yu-Meng Miao; Wen-Xin Yan; Yan-Zhi Geng; Yue Dai; Zhi-Feng Wei
Journal:  Acta Pharmacol Sin       Date:  2021-07-15       Impact factor: 6.150

9.  Long non-coding RNA colorectal neoplasia differentially expressed correlates negatively with miR-33a and miR-495 and positively with inflammatory cytokines in asthmatic children.

Authors:  Weina Li; Xiaoxue Wang; Shixin Sun; Hong An
Journal:  Clin Respir J       Date:  2021-08-22       Impact factor: 1.761

10.  Successful treatment of fatal asthma combined with a silent chest: A case report.

Authors:  Hui Guo; Qian Zhao; Su-Yan Li; Xin Xu; Ning Xu; Chang Lv; Zhang-Shun Shen; Jian-Guo Li
Journal:  J Int Med Res       Date:  2020-05       Impact factor: 1.671

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