| Literature DB >> 27554788 |
Abstract
TplE, a type VI secreted (phospho)lipase, has been identified as the third trans-kingdom effector of Pseudomonas aeruginosa, targeting both prokaryotic and eukaryotic hosts. Indeed, TplE triggers the killing of bacterial competitors and promotes autophagy in epithelial cells once localized to the endoplasmic reticulum.Entities:
Keywords: Pseudomonas aeruginosa; antibacterial; autophagy; endoplasmic reticulum stress; trans-kingdom effector; type VI secretion system
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Year: 2016 PMID： 27554788 DOI： 10.1016/j.tim.2016.08.002
Source DB: PubMed Journal: Trends Microbiol ISSN： 0966-842X Impact factor: 17.079