Literature DB >> 27553969

Iridium(III)-Catalyzed Tandem [3 + 2] Annulation: Synthesis of Spirocyclic Phosphoramide Derivatives.

Shuai-Shuai Li1,2, Lin Wu1, Liu Qin1, Yu-Qin Zhu1, Fu Su1, Yan-Jun Xu3, Lin Dong1.   

Abstract

A highly efficient iridium(III)-catalyzed C-H activation/tandem Grignard-type [3 + 2] annulation process was developed for the synthesis of novel spirocyclic phosphoramide derivatives. Compared with other transition-metal catalysts, [Cp*IrCl2]2 exhibited favorite efficiency and best selectivity in this cascade reaction. The strategy could be applied to further construct more complex heterocyclic compounds.

Entities:  

Year:  2016        PMID： 27553969     DOI： 10.1021/acs.orglett.6b01895

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  2 in total

1.  Rh(iii)-catalyzed synthesis of tetracyclic isoquinolinium salts via C-H activation and [4+2] annulation of 1-phenyl-3,4-dihydroisoquinolines and alkynes in ethanol.

Authors:  Xinxin Dang; Yu He; Yingtian Liu; Xuehong Chen; Jun-Long Li; Xian-Li Zhou; Hezhong Jiang; Jiahong Li
Journal:  RSC Adv       Date:  2018-08-24       Impact factor: 4.036

2.  Base mediated spirocyclization of quinazoline: one-step synthesis of spiro-isoindolinone dihydroquinazolinones.

Authors:  Rapolu Venkateshwarlu; V Narayana Murthy; Krishnaji Tadiparthi; Satish P Nikumbh; Rajesh Jinkala; Vidavalur Siddaiah; M V Madhu Babu; Hindupur Rama Mohan; Akula Raghunadh
Journal:  RSC Adv       Date:  2020-03-04       Impact factor: 4.036
  2 in total

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