Literature DB >> 27551903

A surgical approach in the management of mucormycosis in a trauma patient.

B A Zahoor1,2, J E Piercey3, D R Wall1,2, K D Tetsworth1,2.   

Abstract

Mucormycosis as a consequence of trauma is a devastating complication; these infections are challenging to control, with a fatality rate approaching 96% in immunocompromised patients. We present a case where a proactive approach was successfully employed to treat mucormycosis following complex polytrauma. Aggressive repeated surgical debridement, in combination with appropriate antifungal therapy, proved successful in this instance. In our opinion, mucormycosis in trauma mandates an aggressive surgical approach. This prevents ascending dissemination of mucormycosis and certainly reduces the risk of patient mortality as a direct result. Anti-fungal therapy should be used secondarily as an adjunct together with surgical debridement, or as an alternative when surgical intervention is not feasible.

Entities:  

Keywords:  Invasive fungal wound infection; Mucormycosis; Rhizopus orzaye; Trauma; Treatment

Mesh:

Substances:

Year:  2016        PMID: 27551903      PMCID: PMC5392881          DOI: 10.1308/rcsann.2016.0221

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  9 in total

1.  Lower-extremity zygomycosis in a patient with traumatic injuries. A case report.

Authors:  Ryan C Koonce; Connie S Price; Deanna A Sutton; Brian L Wickes; Paul N Montero; Steven J Morgan
Journal:  J Bone Joint Surg Am       Date:  2009-03-01       Impact factor: 5.284

2.  Mucormycosis complicating lower limb crash injury in a multiple traumatised patient: an unusual case.

Authors:  Mariusz Stasiak; Alfred Samet; Jerzy Lasek; Maria Wujtewicz; Zbigniew Witkowski; Jolanta Komarnicka; Katarzyna Golabek-Dropiewska; Bartosz Rybak; Marta Gross; Wojciech Marks
Journal:  BMJ Case Rep       Date:  2009-04-28

Review 3.  Mucormycosis: its contemporary face and management strategies.

Authors:  Hsin-Yun Sun; Nina Singh
Journal:  Lancet Infect Dis       Date:  2011-04       Impact factor: 25.071

4.  Primary cutaneous mucormycosis: guide to surgical management.

Authors:  Joseph E Losee; Jesse Selber; Stephen Vega; Caroline Hall; Glynis Scott; Joseph M Serletti
Journal:  Ann Plast Surg       Date:  2002-10       Impact factor: 1.539

5.  Recent advances in the treatment of mucormycosis.

Authors:  Brad Spellberg; Ashraf S Ibrahim
Journal:  Curr Infect Dis Rep       Date:  2010-11       Impact factor: 3.725

Review 6.  Mucormycosis in trauma patients.

Authors:  C S Cocanour; P Miller-Crotchett; R L Reed; P C Johnson; R P Fischer
Journal:  J Trauma       Date:  1992-01

7.  Cutaneous mucormycosis and motor vehicle accidents: Findings from an Australian case series.

Authors:  Paul R Ingram; Arul E Suthananthan; Ruben Rajan; Todd M Pryce; Kishore Sieunarine; Dianne J Gardam; Christopher H Heath
Journal:  Med Mycol       Date:  2014-10-06       Impact factor: 4.076

8.  Clinical experience with posaconazole in patients with invasive mucormycosis: a case series.

Authors:  Michelle M González-Ramos; Jorge Bertrán-Pasarell; Humberto Guiot; Ruth Soto; Jorge Santana; Rosana Amador; Ana Conde
Journal:  P R Health Sci J       Date:  2008-12       Impact factor: 0.705

9.  Surgical wound mucormycosis necessitating hand amputation: a case report.

Authors:  H H Chew; A Abuzeid; D Singh; C C Tai
Journal:  J Orthop Surg (Hong Kong)       Date:  2008-08       Impact factor: 1.118

  9 in total
  1 in total

1.  A Surgical Approach in the Management of Mucormycosis in Trauma Patients.

Authors:  Karn Singh; K Jyothirmayee; Ruma Rani; N Surya Vamshi; Mariea Francis; Anagha S Nath
Journal:  J Pharm Bioallied Sci       Date:  2022-07-13
  1 in total

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