Literature DB >> 27549316

Orthostatic hypotension: prevalence and associated risk factors among the ambulatory elderly in an Asian population.

Qing Olivia Zhu1, Choon Seng Gilbert Tan2, Hwee Leong Tan1, Ruining Geraldine Wong1, Chinmaya Shrikant Joshi1, Ravi Amran Cuttilan1, Gek Khim Judy Sng3, Ngiap Chuan Tan4,5.   

Abstract

INTRODUCTION: The prevalence of orthostatic hypotension (OH) among the elderly population in Singapore, as defined by a decline in blood pressure upon a change in position, is not well-established. Studies associate OH with clinically significant outcomes such as falls. This study aims to determine the prevalence of OH among elderly patients attending a public primary care clinic (polyclinic) for chronic disease management, and examine the relationships between postulated risk factors and OH.
METHODS: Patients aged ≥ 65 years attending a typical polyclinic in Geylang were identified and targeted for recruitment at the study site. A questionnaire on symptoms and postulated risk factors was administered, followed by supine and standing blood pressure measurements. Cross-sectional analysis was performed with independent sample t-test for continuous data and chi-square test for categorical data. Prevalence rate ratios with 95% confidence interval were calculated for the latter.
RESULTS: A total of 364 multiethnic patients participated in the study. The prevalence of OH was 11.0%. Older age, comorbidities such as cardiac failure and kidney disease, being physically inactive at work, fatigue, self-reported dizziness in the past year, and the use of loop diuretics were found to be significantly associated with OH.
CONCLUSION: About one in ten elderly patients at a local polyclinic was affected by OH, which was associated with multiple factors. Some of these factors are modifiable and can be addressed to reduce the incidence of OH. Copyright: © Singapore Medical Association.

Entities:  

Keywords:  elderly; orthostatic hypotension; prevalence; primary care

Mesh:

Year:  2016        PMID: 27549316      PMCID: PMC4993969          DOI: 10.11622/smedj.2016135

Source DB:  PubMed          Journal:  Singapore Med J        ISSN: 0037-5675            Impact factor:   1.858


  25 in total

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Journal:  Singapore Med J       Date:  1987-08       Impact factor: 1.858

3.  Orthostatic haemodynamics may be impaired in frailty.

Authors:  Roman Romero-Ortuno; Lisa Cogan; Diarmuid O'Shea; Brian A Lawlor; Rose Anne Kenny
Journal:  Age Ageing       Date:  2011-07-12       Impact factor: 10.668

Review 4.  Pathophysiological basis of orthostatic hypotension in autonomic failure.

Authors:  A A Smit; J R Halliwill; P A Low; W Wieling
Journal:  J Physiol       Date:  1999-08-15       Impact factor: 5.182

5.  Orthostatic hypotension predicts incidence of heart failure: the Malmö preventive project.

Authors:  Artur Fedorowski; Gunnar Engström; Bo Hedblad; Olle Melander
Journal:  Am J Hypertens       Date:  2010-07-22       Impact factor: 2.689

6.  Postural hypotension and dizziness in a general aged population: a four-year follow-up of the Helsinki Aging Study.

Authors:  R S Tilvis; S M Hakala; J Valvanne; T Erkinjuntti
Journal:  J Am Geriatr Soc       Date:  1996-07       Impact factor: 5.562

7.  Standing worsens cognitive functions in patients with neurogenic orthostatic hypotension.

Authors:  R Poda; P Guaraldi; L Solieri; G Calandra-Buonaura; G Marano; R Gallassi; P Cortelli
Journal:  Neurol Sci       Date:  2011-09-06       Impact factor: 3.307

8.  Orthostatic hypotension, hypotension and cognitive status: early comorbid markers of primary dementia?

Authors:  Philip Lin Kiat Yap; Mathew Niti; Keng Bee Yap; Tze Pin Ng
Journal:  Dement Geriatr Cogn Disord       Date:  2008-10-08       Impact factor: 2.959

9.  Population-based study on the prevalence and correlates of orthostatic hypotension/hypertension and orthostatic dizziness.

Authors:  Jin-Shang Wu; Yi-Ching Yang; Feng-Hwa Lu; Chih-Hsing Wu; Chih-Jen Chang
Journal:  Hypertens Res       Date:  2008-05       Impact factor: 3.872

10.  Orthostatic hypotension in healthy elderly: Is it a myth?

Authors:  Rekha Baliga; Girish Prabhu
Journal:  N Am J Med Sci       Date:  2010-09
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  7 in total

1.  Drug-induced orthostatic hypotension: A systematic review and meta-analysis of randomised controlled trials.

Authors:  Cini Bhanu; Danielle Nimmons; Irene Petersen; Mine Orlu; Daniel Davis; Hajra Hussain; Sanuri Magammanage; Kate Walters
Journal:  PLoS Med       Date:  2021-11-09       Impact factor: 11.069

Review 2.  Role of ambulatory blood pressure monitoring in elderly hypertensive patients.

Authors:  Miguel Camafort; Wook-Jin Chung; Jin-Ho Shin
Journal:  Clin Hypertens       Date:  2022-07-01

3.  Health and Functional Determinants of Orthostatic Hypotension in Geriatric Ward Patients: A Retrospective Cross Sectional Cohort Study.

Authors:  Z B Wojszel; A Kasiukiewicz; L Magnuszewski
Journal:  J Nutr Health Aging       Date:  2019       Impact factor: 4.075

4.  Prevalence of postural hypotension in primary, community and institutional care: a systematic review and meta-analysis.

Authors:  Sinead T J McDonagh; Natasha Mejzner; Christopher E Clark
Journal:  BMC Fam Pract       Date:  2021-01-02       Impact factor: 2.497

Review 5.  Initial orthostatic hypotension and orthostatic intolerance symptom prevalence in older adults: A systematic review.

Authors:  Elena M Christopoulos; Jennifer Tran; Sarah L Hillebrand; Peter W Lange; Rebecca K Iseli; Carel G M Meskers; Andrea B Maier
Journal:  Int J Cardiol Hypertens       Date:  2020-12-08

6.  Predictors of Orthostatic Hypotension in the Elderly: Results from the Amirkola Health and Ageing Project (AHAP) Study.

Authors:  Mehdi Safarpour; Akbar Fotouhi; Seyed Reza Hosseini; Masume Mohamadzade; Ali Bijani
Journal:  J Tehran Heart Cent       Date:  2019-10

Review 7.  Prevalence, risk factors, and prognosis of orthostatic hypotension in diabetic patients: A systematic review and meta-analysis.

Authors:  Yu Zhou; Su-Jie Ke; Xiao-Ping Qiu; Li-Bin Liu
Journal:  Medicine (Baltimore)       Date:  2017-09       Impact factor: 1.889

  7 in total

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