Literature DB >> 27549184

Cu-Catalyzed Three-Component Coupling of Aryne, Alkyne, and Benzenesulfonothioate: Modular Synthesis of o-Alkynyl Arylsulfides.

Xianglong Peng1, Chen Ma1, Chen-Ho Tung1, Zhenghu Xu1,2.   

Abstract

A copper-catalyzed three-component coupling reaction of in situ formed arynes, terminal alkynes, and benzenesulfonothioates is described. This reaction provides an efficient modular synthesis of o-alkynyl arylsulfides from easily available starting materials. This process involves one C-S bond and one C-C bond formation in one pot.

Entities:  

Year:  2016        PMID： 27549184     DOI： 10.1021/acs.orglett.6b02027

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  Aryne cycloaddition reactions of benzodioxasilines as aryne precursors generated by catalytic reductive ortho-C-H silylation of phenols with traceless acetal directing groups.

Authors:  Parham Asgari; Udaya Sree Dakarapu; Hiep H Nguyen; Junha Jeon
Journal:  Tetrahedron       Date:  2016-12-08       Impact factor: 2.457

2.  Cu(I)-Catalyzed 1,2-Alkynyl-propargylation and -benzylation of Benzyne Derivatives.

Authors:  Qile Wang; Thomas R Hoye
Journal:  Org Lett       Date:  2021-06-28       Impact factor: 6.072

3.  Mechanistic Study of Copper-Catalyzed C-H Hydroxylation/C-S Coupling by ESI-HR MS and DFT Calculations.

Authors:  Runsheng Xu; Rongrong Cai; Sixian Zhou; Zhuoda Zhou; Beibei Li; Dihui Xu
Journal:  Molecules       Date:  2017-11-06       Impact factor: 4.411
  3 in total

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