Mikhail Kogan1, Carlos Cuellar Castillo1, Melissa S Barber1. 1. Mikhail Kogan, md , is medical director at George Washington University, G. W. Center for Integrative Medicine, in Washington, DC. Carlos Cuellar Castillo, ms , is a graduate of the physiology master of science program and complementary and alternative medicine at Georgetown University, in Washington, DC. Melissa S. Barber, ms , is at Helfgott Research Institute, National University of Natural Medicine, in Portland, Oregon.
Abstract
INTRODUCTION: Chronic rhinosinusitis (CRS) and irritable bowel syndrome (IBS) can be comorbidities that are difficult to treat. In this patient, an evidence-informed treatment pathway guided by laboratory biomarkers was used to address both conditions. CASE PRESENTATION: A 69-y-old female patient presented with a 50-y history of sinusitis that was worse in the winter, postnasal drip, frequent sore throats, gastrointestinal complaints, headaches, and yeast infections. Two sinus surgeries (in years 2000 and 2002) and multiple courses of antibiotics had not resolved her sinus symptoms. In addition to CRS and IBS, this patient was noted to have intestinal overgrowth of Candida albicans, multiple food sensitivities, and leaky gut syndrome. CONCLUSION: Antifungal medication and dietary changes in the course of 8 mo resulted in the resolution of her CRS and IBS.
INTRODUCTION:Chronic rhinosinusitis (CRS) and irritable bowel syndrome (IBS) can be comorbidities that are difficult to treat. In this patient, an evidence-informed treatment pathway guided by laboratory biomarkers was used to address both conditions. CASE PRESENTATION: A 69-y-old female patient presented with a 50-y history of sinusitis that was worse in the winter, postnasal drip, frequent sore throats, gastrointestinal complaints, headaches, and yeast infections. Two sinus surgeries (in years 2000 and 2002) and multiple courses of antibiotics had not resolved her sinus symptoms. In addition to CRS and IBS, this patient was noted to have intestinal overgrowth of Candida albicans, multiple food sensitivities, and leaky gut syndrome. CONCLUSION: Antifungal medication and dietary changes in the course of 8 mo resulted in the resolution of her CRS and IBS.
Authors: Lawrence J Brandt; William D Chey; Amy E Foxx-Orenstein; Lawrence R Schiller; Philip S Schoenfeld; Brennan M Spiegel; Nicholas J Talley; Eamonn M M Quigley Journal: Am J Gastroenterol Date: 2009-01 Impact factor: 10.864
Authors: John S Leeds; Andrew D Hopper; Reena Sidhu; Alison Simmonette; Narges Azadbakht; Nigel Hoggard; Stephen Morley; David S Sanders Journal: Clin Gastroenterol Hepatol Date: 2009-10-14 Impact factor: 11.382
Authors: E A Williams; J Stimpson; D Wang; S Plummer; I Garaiova; M E Barker; B M Corfe Journal: Aliment Pharmacol Ther Date: 2008-09-09 Impact factor: 8.171