Chih-Chung Shiao1, Pei-Chen Wu2, Vin-Cent Wu3, Jui-Hsiang Lin4, Heng-Chih Pan5, Ya-Fei Yang6, Tai-Shuan Lai7, Tao-Min Huang8, Che-Hsiung Wu9, Wei-Shun Yang10, Chih-Jen Wu2, Chih-Chin Kao11, Chiao-Yin Sun5, Chun-Te Huang12, Kuo-Hua Lee13, Chan-Yu Lin14, Te-Chuan Chen15, Fu-Chang Hu16, Hung-Hsiang Liou17, Kuo-Cheng Lu18, Kuo-Liong Chien19, Jian-Jhong Wang20, Wei-Chih Kan21, Feng-Chi Kuo22, Hugo You-Hsien Lin23, Cheng-Min Chen24, Zi-Hong You25, Jen-Pi Tsai26, Chih-Jen Weng27, Hung-Yuan Chen28, Chao-Fu Chang29, Wen-Ding Hsu30, Mai-Szu Wu11, Chiu-Ching Huang6, Kwan-Dun Wu3. 1. Saint Mary's Hospital Luodong and Saint Mary's Medicine, Nursing and Management College, Yilan. 2. Mackay Memorial Hospital. 3. National Taiwan University Hospital. 4. Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan. 5. Keelung Chang Gung Memorial Hospital, Keelung. 6. China Medical University Hospital, Taichung. 7. National Taiwan University Hospital Bei-Hu Branch. 8. National Taiwan University Hospital Yun-Lin Branch, Yunlin County. 9. Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taipei, Taiwan and School of Medicine, Tzu Chi University, Hualien. 10. National Taiwan University Hospital Hisn-Chu Branch, Hsin-Chu City. 11. Taipei Medical University Hospital. 12. Taichung Veteran General Hospital, Taichung. 13. Taipei Veterans General Hospital. 14. Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan. 15. Kaohsiung Chang Gung Memorial Hospital, Kaohsiung and Chang Gung University College of Medicine, Taoyuan. 16. International-Harvard Statistical Consulting Company. 17. Sin-Ren Hospital. 18. Division of Nephrology, Department of Internal Medicine, Cardinal Tien Hospital and School of Medicine, Fu-Jen Catholic University. 19. Graduate Institute of Epidemiology and Preventive Medicine College of Public Health, National Taiwan University. 20. Chi-Mei Medical Center Liouying, Tainan. 21. Chi-Mei Medical Center Yongkang, Tainan. 22. Mackay Memorial Hospital Taitung branch, Taitung. 23. Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung. 24. Lin-Shin Hospital. 25. Taichung Veterans General Hospital Chiayi Branch, Taichung. 26. Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi. 27. Min-Sheng General Hospital, Taoyuan. 28. Far Eastern Memorial Hospital. 29. Taipei City Hospital Heping Branch, Taipei. 30. New Taipei City Hospital Sanchong Branch, New Taipei City, Taiwan.
Abstract
AIM: Acute kidney injury (AKI) carries an increasing incidence rate worldwide and increases the risk of developing end-stage renal disease (ESRD) as well as the medical expenses during the post-AKI course. The Taiwan Consortium for Acute Kidney Injury and Renal Diseases (CAKs) has thus launched a nationwide epidemiology and prognosis of dialysis-requiring acute kidney injury (NEP-AKI-D) study, which prospectively enrols critically ill patients with AKI. Through thoroughly evaluating the risk and prognostic factors of AKI, we hope to lower the incidence of AKI and ESRD from the perspective of AKI-ESRD interaction. METHODS: The CAKs includes 30 hospitals which distribute widely through the four geographical regions (north, middle, south, and east) of Taiwan, and have a 1:1 ratio of medical centres to regional hospitals in each region. The NEP-AKI-D study enrols intensive care unit-based AKI patients who receive dialysis in the four seasonal sampled months (October 2014, along with January, April, and July 2015) in the included hospitals. The collected data include demographic information, pertaining laboratory results, dialysis settings and patient outcomes. The data are uploaded in a centre website and will be audited by on-site principal investigators, computer logic gates, and the CAKs staffs. The outcomes of interest are in-hospital mortality, dialysis-dependency and readmission rate within 90 days after discharge. CONCLUSION: The NEP-AKI-D study enrols a large number of representative AKI patients throughout Taiwan. The results of the current study are expected to provide more insight into the risk and prognostic factors of AKI and further attenuated further chronic kidney disease transition.
AIM: Acute kidney injury (AKI) carries an increasing incidence rate worldwide and increases the risk of developing end-stage renal disease (ESRD) as well as the medical expenses during the post-AKI course. The Taiwan Consortium for Acute Kidney Injury and Renal Diseases (CAKs) has thus launched a nationwide epidemiology and prognosis of dialysis-requiring acute kidney injury (NEP-AKI-D) study, which prospectively enrols critically ill patients with AKI. Through thoroughly evaluating the risk and prognostic factors of AKI, we hope to lower the incidence of AKI and ESRD from the perspective of AKI-ESRD interaction. METHODS: The CAKs includes 30 hospitals which distribute widely through the four geographical regions (north, middle, south, and east) of Taiwan, and have a 1:1 ratio of medical centres to regional hospitals in each region. The NEP-AKI-D study enrols intensive care unit-based AKI patients who receive dialysis in the four seasonal sampled months (October 2014, along with January, April, and July 2015) in the included hospitals. The collected data include demographic information, pertaining laboratory results, dialysis settings and patient outcomes. The data are uploaded in a centre website and will be audited by on-site principal investigators, computer logic gates, and the CAKs staffs. The outcomes of interest are in-hospital mortality, dialysis-dependency and readmission rate within 90 days after discharge. CONCLUSION: The NEP-AKI-D study enrols a large number of representative AKI patients throughout Taiwan. The results of the current study are expected to provide more insight into the risk and prognostic factors of AKI and further attenuated further chronic kidney disease transition.