Literature DB >> 27545968

Minimizing osteoradionecrosis after mandibular reconstruction and radiation in advanced head and neck cancer patients.

Emre Gazyakan1,2, Chih-Wei Wu1,3, Jung-Ju Huang1,3, Holger Engel1,4, Ian Lee Valerio1,5, Ming-Huei Cheng1,3.   

Abstract

BACKGROUND: Osteoradionecrosis may develop on the residual mandible or reconstructed fibula because of inadequate soft tissue coverage and compromised tissue perfusion post mandibular reconstruction, and radiation. This study was to investigate the incidence of osteoradionecrosis following class III mandibular defect reconstructions with an OPAC flap versus a fibula OSC flap.
METHODS: A retrospective review of a consecutive series of mandibular reconstructions between 1999 and 2010 was performed. Mandibular defects and corresponding flap types were analyzed with emphasis on outcome, complications, and rates of osteoradionecrosis among the two subgroups.
RESULTS: A total of 121 fibula flaps were performed, consisting of 53 OPAC and 68 fibula OSC flaps. Complications trended higher for OPAC flaps in partial and total flap loss rates as well as venous congestion when compared with the OSC flap cohort. The OPAC group had statistically significant lower rates of osteoradionecrosis and plate exposure than the OSC group (P = 0.04).
CONCLUSION: The OPAC flap may be preferable to fibula OSC flap in mandibular reconstruction given its lower rates of osteoradionecrosis and plate exposure. This flap type may be the flap of choice for class III defects where additional vascularized tissue may be critical for addressing significant soft tissue deficiency. J. Surg. Oncol. 2016;114:399-404.
© 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Entities:  

Keywords:  fibula flap; mandible reconstruction; osteoradionecrosis; peroneal artery perforator flap; plate exposure

Mesh:

Year:  2016        PMID: 27545968     DOI: 10.1002/jso.24321

Source DB:  PubMed          Journal:  J Surg Oncol        ISSN: 0022-4790            Impact factor:   3.454


  2 in total

Review 1.  Mini-plate versus reconstruction bar fixation for oncologic mandibular reconstruction with free fibula flaps: A systematic review and meta-analysis.

Authors:  Nikhil Sobti; Kaleem S Ahmed; Thais Polanco; Marina Chilov; Marc A Cohen; Jay Boyle; Farooq Shahzad; Evan Matros; Jonas A Nelson; Robert J Allen
Journal:  J Plast Reconstr Aesthet Surg       Date:  2022-05-06       Impact factor: 3.022

2.  The Impact of Postoperative Radiotherapy on Dietary Function of Head and Neck Cancer Patients after Pharyngoesophageal Reconstruction with Free Jejunal Flap.

Authors:  Lan Sook Chang; Hyun Wang; Hee Chang Ahn; Tae Hyeon Lee; Kyung Tae; Seong Oh Park
Journal:  J Clin Med       Date:  2022-05-19       Impact factor: 4.964

  2 in total

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