| Literature DB >> 27545588 |
Vijay S Vyas1, Medhavi Vishwakarma2,3, Igor Moudrakovski1, Frederik Haase1,4, Gökcen Savasci4, Christian Ochsenfeld4,5, Joachim P Spatz2,3, Bettina V Lotsch6,7.
Abstract
Covalent organic frameworks (COFs) are a new class of nanoporous polymeric vector showing promise as drug-delivery vehicles with high loading capacity and biocompatibility. The interaction between the carrier and the cargo is specifically tailored on a molecular level by H-bonding. Cell-proliferation studies indicate higher efficacy of the drug in cancer cells by nanocarrier delivery mediated by the COF.Entities:
Keywords: covalent organic frameworks; drug delivery; molecular dynamics; porous materials; supramolecular chemistry
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Year: 2016 PMID: 27545588 DOI: 10.1002/adma.201603006
Source DB: PubMed Journal: Adv Mater ISSN: 0935-9648 Impact factor: 30.849