| Literature DB >> 27540902 |
Liverana Lauretti1, Quintino Giorgio D'Alessandris1, Massimo Fantoni2, Tiziana D'Inzeo3, Eduardo Fernandez1, Roberto Pallini1, Giancarlo Scoppettuolo2.
Abstract
The authors report on the first case of the intraventricular administration of tigecycline described in the Western literature. A 22-year-old man developed cerebrospinal fluid infection from an extremely drug-resistant strain of Acinetobacter baumannii as a complication of endoscopic transsphenoidal surgery for the removal of a giant pituitary adenoma. The patient was safely and successfully treated with the prolonged intraventricular administration of tigecycline. Here, the authors provide the schedule details that can be invaluable in treating meningitis from extremely drug-resistant bacterial strains. Intraventricular tigecycline can be a valuable tool against multidrug-resistant central nervous system infections.Entities:
Keywords: Acinetobacter; CNS = central nervous system; CSF = cerebrospinal fluid; IV = intravenous; IVT = intraventricular; MDR = multidrug resistant; XDR = extremely drug resistant; infection; intraventricular therapy; meningitis; tigecycline; transsphenoidal surgery
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Year: 2016 PMID： 27540902 DOI： 10.3171/2016.6.JNS16352
Source DB: PubMed Journal: J Neurosurg ISSN： 0022-3085 Impact factor: 5.115