Literature DB >> 27539537

Substance P and sickle cell disease-a marker for pain and novel therapeutic approaches.

Steven D Douglas1.   

Abstract

Entities:  

Keywords:  aprepitant; neurokinin 1 antagonist; pain; sickle cell disease; substance P

Mesh：

Substances：

Year:  2016        PMID： 27539537      PMCID： PMC5063693          DOI： 10.1111/bjh.14299

Source DB:  PubMed          Journal:  Br J Haematol        ISSN： 0007-1048            Impact factor:   6.998


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  13 in total

1.  Spinal glial activation and oxidative stress are alleviated by treatment with curcumin or coenzyme Q in sickle mice.

Authors:  Yessenia Valverde; Barbara Benson; Mihir Gupta; Kalpna Gupta
Journal:  Haematologica       Date:  2015-11-06       Impact factor: 9.941

2.  Small-molecule nociceptin receptor agonist ameliorates mast cell activation and pain in sickle mice.

Authors:  Derek Vang; Jinny A Paul; Julia Nguyen; Huy Tran; Lucile Vincent; Dennis Yasuda; Nurulain T Zaveri; Kalpna Gupta
Journal:  Haematologica       Date:  2015-08-20       Impact factor: 9.941

Review 3.  Neurokinin-1 receptor: functional significance in the immune system in reference to selected infections and inflammation.

Authors:  Steven D Douglas; Susan E Leeman
Journal:  Ann N Y Acad Sci       Date:  2010-11-22       Impact factor: 5.691

4.  Elevated plasma substance P in sickle cell disease and vaso-occlusive crisis.

Authors:  Steven D Douglas
Journal:  Med Hypotheses       Date:  2008-02-14       Impact factor: 1.538

Review 5.  Early insights into the neurobiology of pain in sickle cell disease: A systematic review of the literature.

Authors:  Amanda M Brandow; Rebecca A Farley; Julie A Panepinto
Journal:  Pediatr Blood Cancer       Date:  2015-05-13       Impact factor: 3.167

6.  HIV infection of macrophages is enhanced in the presence of increased expression of CD163 induced by substance P.

Authors:  Florin Tuluc; John Meshki; Sergei Spitsin; Steven D Douglas
Journal:  J Leukoc Biol       Date:  2014-02-27       Impact factor: 4.962

7.  Mast cell activation contributes to sickle cell pathobiology and pain in mice.

Authors:  Lucile Vincent; Derek Vang; Julia Nguyen; Mihir Gupta; Kathryn Luk; Marna E Ericson; Donald A Simone; Kalpna Gupta
Journal:  Blood       Date:  2013-06-17       Impact factor: 22.113

8.  Serum levels of substance P are elevated in patients with sickle cell disease and increase further during vaso-occlusive crisis.

Authors:  L A Michaels; K Ohene-Frempong; H Zhao; S D Douglas
Journal:  Blood       Date:  1998-11-01       Impact factor: 22.113

9.  Pharmacologic rationale for the NK1R antagonist, aprepitant as adjunctive therapy in HIV.

Authors:  Jeffrey S Barrett; Sergei Spitsin; Ganesh Moorthy; Kyle Barrett; Kate Baker; Andrew Lackner; Florin Tulic; Angela Winters; Dwight L Evans; Steven D Douglas
Journal:  J Transl Med       Date:  2016-05-26       Impact factor: 5.531

10.  Reduction of soluble CD163, substance P, programmed death 1 and inflammatory markers: phase 1B trial of aprepitant in HIV-1-infected adults.

Authors:  Pablo Tebas; Sergei Spitsin; Jeffrey S Barrett; Florin Tuluc; Okan Elci; James J Korelitz; Wayne Wagner; Angela Winters; Deborah Kim; Renae Catalano; Dwight L Evans; Steven D Douglas
Journal:  AIDS       Date:  2015-05-15       Impact factor: 4.177
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  4 in total

Review 1.  Mast cell-neural interactions contribute to pain and itch.

Authors:  Kalpna Gupta; Ilkka T Harvima
Journal:  Immunol Rev       Date:  2018-03       Impact factor: 12.988

2.  End points for sickle cell disease clinical trials: patient-reported outcomes, pain, and the brain.

Authors:  Ann T Farrell; Julie Panepinto; C Patrick Carroll; Deepika S Darbari; Ankit A Desai; Allison A King; Robert J Adams; Tabitha D Barber; Amanda M Brandow; Michael R DeBaun; Manus J Donahue; Kalpna Gupta; Jane S Hankins; Michelle Kameka; Fenella J Kirkham; Harvey Luksenburg; Shirley Miller; Patricia Ann Oneal; David C Rees; Rosanna Setse; Vivien A Sheehan; John Strouse; Cheryl L Stucky; Ellen M Werner; John C Wood; William T Zempsky
Journal:  Blood Adv       Date:  2019-12-10

Review 3.  Toward Composite Pain Biomarkers of Neuropathic Pain-Focus on Peripheral Neuropathic Pain.

Authors:  Monica M Diaz; Jacob Caylor; Irina Strigo; Imanuel Lerman; Brook Henry; Eduardo Lopez; Mark S Wallace; Ronald J Ellis; Alan N Simmons; John R Keltner
Journal:  Front Pain Res (Lausanne)       Date:  2022-05-11

4.  Mast Cells Induce Blood Brain Barrier Damage in SCD by Causing Endoplasmic Reticulum Stress in the Endothelium.

Authors:  Huy Tran; Aditya Mittal; Varun Sagi; Kathryn Luk; Aithanh Nguyen; Mihir Gupta; Julia Nguyen; Yann Lamarre; Jianxun Lei; Alonso Guedes; Kalpna Gupta
Journal:  Front Cell Neurosci       Date:  2019-02-19       Impact factor: 5.505
  4 in total

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