Literature DB >> 27539056

Overview of Oroxylin A: A Promising Flavonoid Compound.

Lu Lu1, Qinglong Guo2, Li Zhao3.   

Abstract

Oroxylin A is one of the main active components extracted from Scutellariae radix. It has been proved that oroxylin A possesses a broad spectrum of pharmacological functions, including anti-cancer, antiinflammation, neuroprotective, anti-coagulation and so on. The pharmacological activity of oroxylin A has been studied in vitro and on animal models, which reflected its promising potency in disease treatment. This review aims to recapitulate the pharmacological function and the molecular mechanisms of oroxylin A, as well as its sources, extraction, synthesis and toxicity study. These data confirmed the therapeutic potential of oroxylin A and provided reference for further development.
Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

Entities:  

Keywords:  anti-cancer; oroxylin A; pharmacological activity; review

Mesh:

Substances:

Year:  2016        PMID: 27539056     DOI: 10.1002/ptr.5694

Source DB:  PubMed          Journal:  Phytother Res        ISSN: 0951-418X            Impact factor:   5.878


  19 in total

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6.  Oroxylin A inhibits the migration of hepatocellular carcinoma cells by inducing NAG-1 expression.

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Review 10.  Apoptosis Exerts a Vital Role in the Treatment of Colitis-Associated Cancer by Herbal Medicine.

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Journal:  Front Pharmacol       Date:  2020-04-28       Impact factor: 5.810

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