Literature DB >> 27536569

Deep Vein Thrombosis in a Patient with Polycythemia Vera Who Underwent Hip Surgery: A Case Report.

Yong Sik Lee1, Byung Ho Seo1, Soo Won Lee1, Sung Hwan Kim1, Byung Kil Ahn1.   

Abstract

A 68-year-old woman who suffered from polycythemia vera presented at our clinic with the chief complaints of pain, swelling, and a warm sensation in her left thigh. She had undergone a left bipolar hemiarthroplasty following a hip fracture 24 days prior to this presentation. Her erythrocyte sedimentation rate and C-reactive protein (CRP) levels were elevated. In addition, a postoperative infection was suspected in the 3-phase bone scan; therefore, she received intravenous antibiotic therapy. This approach proved to be ineffective and she was subsequently diagnosed with a deep vein thrombosis via color Doppler ultrasonography. It is interesting to note that a deep vein thrombosis can present with symptoms similar to those of a postoperative infection. Furthermore, an elevated CRP level is frequently observed in patients suffering from polycythemia vera. Therefore, the two conditions, which require completely different treatments, can be confused. We report on this case with a review of the relevant literature.

Entities:  

Keywords:  Deep vein thrombosis; Polycythemia vera; Postoperative infection

Year:  2014        PMID: 27536569      PMCID: PMC4971116          DOI: 10.5371/hp.2014.26.2.124

Source DB:  PubMed          Journal:  Hip Pelvis        ISSN: 2287-3260


  8 in total

1.  Increased platelet activation and abnormal membrane glycoprotein content and redistribution in myeloproliferative disorders.

Authors:  M K Jensen; P de Nully Brown; B V Lund; O J Nielsen; H C Hasselbalch
Journal:  Br J Haematol       Date:  2000-07       Impact factor: 6.998

2.  A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. The Worcester DVT Study.

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Authors:  Edith M Roumen-Klappe; Martin den Heijer; Stan H M van Uum; Johanna van der Ven-Jongekrijg; Fedde van der Graaf; Hub Wollersheim
Journal:  J Vasc Surg       Date:  2002-04       Impact factor: 4.268

Review 4.  Hyperviscosity in polycythemia vera and other red cell abnormalities.

Authors:  Hau C Kwaan; Jun Wang
Journal:  Semin Thromb Hemost       Date:  2003-10       Impact factor: 4.180

5.  Plasma interleukin-6 and C-reactive protein levels in reactive versus clonal thrombocytosis.

Authors:  A Tefferi; T C Ho; G J Ahmann; J A Katzmann; P R Greipp
Journal:  Am J Med       Date:  1994-10       Impact factor: 4.965

6.  C-reactive protein (CRP) levels after elective orthopedic surgery.

Authors:  S Larsson; U Thelander; S Friberg
Journal:  Clin Orthop Relat Res       Date:  1992-02       Impact factor: 4.176

7.  Death and thromboembolic disease after total hip replacement. A series of 1162 cases with no routine chemical prophylaxis.

Authors:  D Warwick; M H Williams; G C Bannister
Journal:  J Bone Joint Surg Br       Date:  1995-01

8.  The value of serum procalcitonin level for differentiation of infectious from noninfectious causes of fever after orthopaedic surgery.

Authors:  Sabina Hunziker; Thomas Hügle; Katrin Schuchardt; Isabelle Groeschl; Philipp Schuetz; Beat Mueller; Walter Dick; Urs Eriksson; Andrej Trampuz
Journal:  J Bone Joint Surg Am       Date:  2010-01       Impact factor: 5.284

  8 in total

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