Literature DB >> 27535897

Drug Delivery by Controlling a Supramolecular Host-Guest Assembly with a Reversible Photoswitch.

Nuno Basílio1, Uwe Pischel2.   

Abstract

The reversibly switchable trans-chalcone/flavylium photochromic system was successfully coupled to the complexation equilibrium of a drug-cucurbit[7]uril host-guest assembly. Hence, the phototriggered release of memantine under illumination at 366 nm was observed. The process can be partially reverted through a thermally activated back reaction.
© 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  cucurbiturils; drug delivery; flavylium; host-guest chemistry; photochemistry

Year:  2016        PMID： 27535897     DOI： 10.1002/chem.201603331

Source DB:  PubMed          Journal:  Chemistry        ISSN： 0947-6539            Impact factor:   5.236


  6 in total

1.  Exploring pH Dependent Host/Guest Binding Affinities.

Authors:  Thomas J Paul; Jonah Z Vilseck; Ryan L Hayes; Charles L Brooks
Journal:  J Phys Chem B       Date:  2020-07-22       Impact factor: 2.991

2.  Five-Component Self-Assembly of Cucurbituril-Based Hetero-pseudorotaxanes.

Authors:  Cátia Parente Carvalho; Zoe Domínguez; Cristina Domínguez; Hamdy S El-Sheshtawy; José Paulo Da Silva; Jesús F Arteaga; Uwe Pischel
Journal:  ChemistryOpen       Date:  2017-03-10       Impact factor: 2.911

3.  Host-guest complexes of imazalil with cucurbit[8]uril and β-cyclodextrin and their effect on plant pathogenic fungi.

Authors:  Naji Al-Dubaili; Khaled El-Tarabily; Na'il Saleh
Journal:  Sci Rep       Date:  2018-02-12       Impact factor: 4.379

4.  Supramolecular Chemistry Targeting Proteins.

Authors:  Sam van Dun; Christian Ottmann; Lech-Gustav Milroy; Luc Brunsveld
Journal:  J Am Chem Soc       Date:  2017-09-28       Impact factor: 15.419

Review 5.  Applications of Cucurbiturils in Medicinal Chemistry and Chemical Biology.

Authors:  Debapratim Das; Khaleel I Assaf; Werner M Nau
Journal:  Front Chem       Date:  2019-09-13       Impact factor: 5.221

6.  Toward Light-Controlled Supramolecular Peptide Dimerization.

Authors:  Rita J Fernandes; Patricia Remón; Artur J Moro; André Seco; Ana S D Ferreira; Uwe Pischel; Nuno Basílio
Journal:  J Org Chem       Date:  2021-06-01       Impact factor: 4.198
  6 in total

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