BACKGROUND: The current study evaluated the usefulness of a belt technique for restricting respiratory motion of the heart and for improving image quality of 13N-ammonia myocardial PET/CT, and it assessed the tolerability of the belt technique in the clinical setting. METHODS: Myocardial 13N-ammonia PET/CT scanning was performed in 8 volunteers on Discovery PET/CT 690 with an optical respiratory motion tracking system. Emission scans were performed with and without an abdominal belt. The amplitude of left ventricular (LV) respiratory motion was measured on respiratory-gated PET images. The degree of erroneous decreases in regional myocardial uptake was visually assessed on ungated PET images using a 5-point scale (0 = normal, 1/2/3 = mild/moderate/severe decrease, 4 = defect). The tolerability of the belt technique was evaluated in 53 patients. RESULTS: All subjects tolerated the belt procedure. The amplitude of the LV respiratory motion decreased significantly with the belt (8.1 ± 7.1 vs 12.1 ± 6.1 mm, P = .0078). The belt significantly improved the image quality scores in the anterior (0.29 ± 0.81 vs 0.71 ± 1.04, P = .015) and inferior (0.33 ± 0.92 vs 1.04 ± 1.04, P < .0001) wall. No adverse events related to the belt technique were observed. CONCLUSIONS: The belt technique restricts LV respiratory motion and improves the image quality of myocardial PET/CT, and it is well tolerated by patients.
BACKGROUND: The current study evaluated the usefulness of a belt technique for restricting respiratory motion of the heart and for improving image quality of 13N-ammonia myocardial PET/CT, and it assessed the tolerability of the belt technique in the clinical setting. METHODS: Myocardial 13N-ammonia PET/CT scanning was performed in 8 volunteers on Discovery PET/CT 690 with an optical respiratory motion tracking system. Emission scans were performed with and without an abdominal belt. The amplitude of left ventricular (LV) respiratory motion was measured on respiratory-gated PET images. The degree of erroneous decreases in regional myocardial uptake was visually assessed on ungated PET images using a 5-point scale (0 = normal, 1/2/3 = mild/moderate/severe decrease, 4 = defect). The tolerability of the belt technique was evaluated in 53 patients. RESULTS: All subjects tolerated the belt procedure. The amplitude of the LV respiratory motion decreased significantly with the belt (8.1 ± 7.1 vs 12.1 ± 6.1 mm, P = .0078). The belt significantly improved the image quality scores in the anterior (0.29 ± 0.81 vs 0.71 ± 1.04, P = .015) and inferior (0.33 ± 0.92 vs 1.04 ± 1.04, P < .0001) wall. No adverse events related to the belt technique were observed. CONCLUSIONS: The belt technique restricts LV respiratory motion and improves the image quality of myocardial PET/CT, and it is well tolerated by patients.
Authors: Luyao Shi; Yihuan Lu; Nicha Dvornek; Christopher A Weyman; Edward J Miller; Albert J Sinusas; Chi Liu Journal: IEEE Trans Med Imaging Date: 2021-11-30 Impact factor: 10.048