Mads E Jørgensen1, Charlotte Andersson2, Anne-Marie Schjerning Olsen2, Knud Juel3, Poul Erik Mortensen4, Erik Jørgensen5, Hans-Henrik Tilsted6, Lene Mia von Kappelgaard3, Christian Torp-Pedersen7, Gunnar H Gislason8. 1. The Cardiovascular Research Center, Gentofte University Hospital, Hellerup, Denmark National Institute of Public Health, University of Southern Denmark, Odense, Denmark mads.emil.joergensen@regionh.dk. 2. The Cardiovascular Research Center, Gentofte University Hospital, Hellerup, Denmark. 3. National Institute of Public Health, University of Southern Denmark, Odense, Denmark. 4. Odense University Hospital, University of Southern Denmark, Odense, Denmark. 5. Department of Cardiology, The Heart Center, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. 6. Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark. 7. Department of Health Science and Technology, Aalborg University, Aalborg, Denmark. 8. The Cardiovascular Research Center, Gentofte University Hospital, Hellerup, Denmark National Institute of Public Health, University of Southern Denmark, Odense, Denmark.
Abstract
AIMS: Coronary angiography holds a central role in the diagnosis of coronary heart disease. We studied temporal trends in referral patterns 2000-09. METHODS AND RESULTS: We identified 156 496 first-time coronary angiographies in 2000-09 in nationwide registries. Trends were analyzed in 2-year intervals. Numbers of acute (5943-10 707) and elective (17 294-25 550) procedures increased between 2000-01 and 2008-09. Mean age increased from 61.8 to 63.9 years (P < 0.001) and the proportion of females increased from 33 to 37% (P < 0.001). An increase in the number of patients with prior chronic heart failure (2866 vs. 3197), cerebrovascular disease (1790 vs. 2906), diabetes (2527 vs. 4593), and arrhythmias (2985 vs. 4733) was observed. The proportion of acute patients examined the same day as hospitalized increased from 56.6 to 83.1%. Odds ratios (95% confidence interval) for treatment with statins [3.42(3.27;3.57)], RAS-inhibitors [1.85(1.77;1.93)], and acetylsalicylic acid [1.43(1.37;1.49)] at the time of coronary angiography increased towards 2008-09. Elective patients received medical treatment more often than acute patients (P < 0.001). CONCLUSION: During a 10-year period, there was an increase in the mean age of patients and the proportion of female patients, and a 56% increase in number of coronary angiographies performed. The use of prophylactic cardiovascular drugs among these high-risk patients increased during our study period. Published on behalf of the European Society of Cardiology. All rights reserved.
AIMS: Coronary angiography holds a central role in the diagnosis of coronary heart disease. We studied temporal trends in referral patterns 2000-09. METHODS AND RESULTS: We identified 156 496 first-time coronary angiographies in 2000-09 in nationwide registries. Trends were analyzed in 2-year intervals. Numbers of acute (5943-10 707) and elective (17 294-25 550) procedures increased between 2000-01 and 2008-09. Mean age increased from 61.8 to 63.9 years (P < 0.001) and the proportion of females increased from 33 to 37% (P < 0.001). An increase in the number of patients with prior chronic heart failure (2866 vs. 3197), cerebrovascular disease (1790 vs. 2906), diabetes (2527 vs. 4593), and arrhythmias (2985 vs. 4733) was observed. The proportion of acute patients examined the same day as hospitalized increased from 56.6 to 83.1%. Odds ratios (95% confidence interval) for treatment with statins [3.42(3.27;3.57)], RAS-inhibitors [1.85(1.77;1.93)], and acetylsalicylic acid [1.43(1.37;1.49)] at the time of coronary angiography increased towards 2008-09. Elective patients received medical treatment more often than acute patients (P < 0.001). CONCLUSION: During a 10-year period, there was an increase in the mean age of patients and the proportion of female patients, and a 56% increase in number of coronary angiographies performed. The use of prophylactic cardiovascular drugs among these high-risk patients increased during our study period. Published on behalf of the European Society of Cardiology. All rights reserved.
Authors: Jari Heiskanen; Juha Hartikainen; Janne Martikainen; Heikki Miettinen; Mikko Hippeläinen; Risto P Roine; Anna-Maija Tolppanen Journal: Eur J Clin Pharmacol Date: 2019-10-11 Impact factor: 2.953
Authors: Daniel Mølager Christensen; Matthew Phelps; Thomas Gerds; Morten Malmborg; Anne-Marie Schjerning; Jarl Emanuel Strange; Mohamad El-Chouli; Lars Bruun Larsen; Emil Fosbøl; Lars Køber; Christian Torp-Pedersen; Suneela Mehta; Rod Jackson; Gunnar Gislason Journal: Eur Heart J Open Date: 2021-08-02