Literature DB >> 27530228

Hemozoin detection may provide an inexpensive, sensitive, 1-minute malaria test that could revolutionize malaria screening.

Brian T Grimberg1, Kerry O Grimberg2.   

Abstract

Malaria remains widespread throughout the tropics and is a burden to the estimated 3.5 billion people who are exposed annually. The lack of a fast and accurate diagnostic method contributes to preventable malaria deaths and its continued transmission. In many areas diagnosis is made solely based on clinical presentation. Current methods for malaria diagnosis take more than 20 minutes from the time blood is drawn and are frequently inaccurate. The introduction of an accurate malaria diagnostic that can provide a result in less than 1 minute would allow for widespread screening and treatment of endemic populations, and enable regions that have gained a foothold against malaria to prevent its return. Using malaria parasites' waste product, hemozoin, as a biomarker for the presence of malaria could be the tool needed to develop this rapid test.

Entities:  

Keywords:  Magneto-Optical Detection; Malaria; RDT; elimination; hemozoin; rapid diagnostic

Mesh:

Substances:

Year:  2016        PMID: 27530228      PMCID: PMC5224914          DOI: 10.1080/14787210.2016.1222900

Source DB:  PubMed          Journal:  Expert Rev Anti Infect Ther        ISSN: 1478-7210            Impact factor:   5.091


  31 in total

1.  Sensitive DNA detection and SNP discrimination using ultrabright SERS nanorattles and magnetic beads for malaria diagnostics.

Authors:  Hoan T Ngo; Naveen Gandra; Andrew M Fales; Steve M Taylor; Tuan Vo-Dinh
Journal:  Biosens Bioelectron       Date:  2016-01-29       Impact factor: 10.618

2.  Detection of Plasmodium falciparum in pregnancy by laser desorption mass spectrometry.

Authors:  Myaing Nyunt; John Pisciotta; Andrew B Feldman; Philip Thuma; Peter F Scholl; Plamen A Demirev; Jeffrey S Lin; Lirong Shi; Nirbhay Kumar; David J Sullivan
Journal:  Am J Trop Med Hyg       Date:  2005-09       Impact factor: 2.345

3.  Clearance kinetics of parasites and pigment-containing leukocytes in severe malaria.

Authors:  N P Day; T D Pham; T L Phan; X S Dinh; P L Pham; V C Ly; T H Tran; T H Nguyen; D B Bethell; H P Nguyan; T H Tran; N J White
Journal:  Blood       Date:  1996-12-15       Impact factor: 22.113

4.  A magneto-optic route toward the in vivo diagnosis of malaria: preliminary results and preclinical trial data.

Authors:  Dave M Newman; John Heptinstall; Raphael J Matelon; Luke Savage; M Lesley Wears; Jamie Beddow; Martin Cox; Henk D F H Schallig; Petra F Mens
Journal:  Biophys J       Date:  2008-04-04       Impact factor: 4.033

5.  Laboratory evaluation on the sensitivity and specificity of a novel and rapid detection method for malaria diagnosis based on magneto-optical technology (MOT).

Authors:  Petra F Mens; Raphael J Matelon; Bakri Y M Nour; Dave M Newman; Henk D F H Schallig
Journal:  Malar J       Date:  2010-07-19       Impact factor: 2.979

6.  Transdermal Diagnosis of Malaria Using Vapor Nanobubbles.

Authors:  Ekaterina Lukianova-Hleb; Sarah Bezek; Reka Szigeti; Alexander Khodarev; Thomas Kelley; Andrew Hurrell; Michail Berba; Nirbhay Kumar; Umberto D'Alessandro; Dmitri Lapotko
Journal:  Emerg Infect Dis       Date:  2015-07       Impact factor: 6.883

7.  A simplified, low-cost method for polarized light microscopy.

Authors:  Richard J Maude; Wanchana Buapetch; Kamolrat Silamut
Journal:  Am J Trop Med Hyg       Date:  2009-11       Impact factor: 2.345

8.  Pilot assessment of the sensitivity of the malaria thin film.

Authors:  Colin Ohrt; Wendy Prudhomme O'Meara; Shon Remich; Peter McEvoy; Bernhards Ogutu; Ramadan Mtalib; James Sande Odera
Journal:  Malar J       Date:  2008-01-28       Impact factor: 2.979

9.  Enhanced detection of gametocytes by magnetic deposition microscopy predicts higher potential for Plasmodium falciparum transmission.

Authors:  Stephan Karl; Makindi David; Lee Moore; Brian T Grimberg; Pascal Michon; Ivo Mueller; Maciej Zborowski; Peter A Zimmerman
Journal:  Malar J       Date:  2008-04-25       Impact factor: 2.979

10.  Lessons learned from the use of HRP-2 based rapid diagnostic test in community-wide screening and treatment of asymptomatic carriers of Plasmodium falciparum in Burkina Faso.

Authors:  Alfred B Tiono; Alphonse Ouédraogo; Amidou Diarra; Sam Coulibaly; Issiaka Soulama; Amadou T Konaté; Aïssata Barry; Amitava Mukhopadhyay; Sodiomon B Sirima; Kamal Hamed
Journal:  Malar J       Date:  2014-01-27       Impact factor: 2.979

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  5 in total

1.  An ON-OFF Magneto-Optical Probe of Anisotropic Biofluid Crystals: A β-Hematin Case Study.

Authors:  Danielle Kara; Robert J Deissler; Rose Al Helo; Kyle Blasinsky; Brian T Grimberg; Robert Brown
Journal:  IEEE Trans Magn       Date:  2021-07-09       Impact factor: 1.848

Review 2.  Recent Progress in the Development of Diagnostic Tests for Malaria.

Authors:  Francis D Krampa; Yaw Aniweh; Gordon A Awandare; Prosper Kanyong
Journal:  Diagnostics (Basel)       Date:  2017-09-19

Review 3.  Review of Microdevices for Hemozoin-Based Malaria Detection.

Authors:  Vitória Baptista; Weng Kung Peng; Graça Minas; Maria Isabel Veiga; Susana O Catarino
Journal:  Biosensors (Basel)       Date:  2022-02-11

4.  On-chip magnetophoretic capture in a model of malaria-infected red blood cells.

Authors:  Marco Giacometti; Marco Monticelli; Marco Piola; Francesca Milesi; Lorenzo P Coppadoro; Enrico Giuliani; Emanuela Jacchetti; Manuela T Raimondi; Giorgio Ferrari; Spinello Antinori; Gianfranco B Fiore; Riccardo Bertacco
Journal:  Biotechnol Bioeng       Date:  2022-01-25       Impact factor: 4.395

5.  Growth of Plasmodium falciparum in response to a rotating magnetic field.

Authors:  Rebecca C Gilson; Robert J Deissler; Richard F Bihary; William C Condit; Mary E Thompson; D'Arbra Blankenship; Kerry O Grimberg; Robert W Brown; Brian T Grimberg
Journal:  Malar J       Date:  2018-05-03       Impact factor: 2.979

  5 in total

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