Literature DB >> 27528845

Staged Soft Tissue Reconstruction Following Sarcoma Excision with Anticipated Large Cutaneous Defects: An Oncologically Safe Alternative.

Geoffrey W Siegel1, William M Kuzon2, Jill M Hasen3, J Sybil Biermann3.   

Abstract

BACKGROUND: We hypothesized that select patients undergoing planned soft tissue sarcoma (STS) excision with anticipated skin and soft tissue deficits could be treated with a two stage surgical procedure which would allow some flexibility in coverage options while not significantly increasing local recurrence rate or wound complication rate.
METHODS: A retrospective review was undertaken in a series of consecutive patients with a minimum 2-year follow-up treated by a single orthopedic oncologist and a single reconstructive plastic surgeon who were managed with a staged approach STS excision and reconstruction.
RESULTS: There were 73 patients identified over a ten-year period that underwent staged STS excision and soft tissue reconstruction. There were 12 (16%) initial positive margins resected to negative final margins, and a variety of coverage procedures performed. Wound complication rate was 21%. Local recurrence rate was 11%.
CONCLUSION: Staged STS excision and reconstruction is an acceptable tool in the armamentarium of the orthopedic oncologist for managing major soft tissue deficits without an increase in local recurrence rates.

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Mesh:

Year:  2016        PMID: 27528845      PMCID: PMC4910795     

Source DB:  PubMed          Journal:  Iowa Orthop J        ISSN: 1541-5457


  22 in total

1.  Outcomes of re-excision after unplanned excisions of soft-tissue sarcomas.

Authors:  Mark W Manoso; Deborah A Frassica; E Gene Deune; Frank J Frassica
Journal:  J Surg Oncol       Date:  2005-09-01       Impact factor: 3.454

2.  Accuracy of frozen section diagnosis in soft tissue tumors.

Authors:  R Golouh; M Bracko
Journal:  Mod Pathol       Date:  1990-11       Impact factor: 7.842

3.  Efficacy of adjuvant radiation therapy in the treatment of soft tissue sarcoma of the extremity: 20-year follow-up of a randomized prospective trial.

Authors:  Joal D Beane; James C Yang; Donald White; Seth M Steinberg; Steven A Rosenberg; Udo Rudloff
Journal:  Ann Surg Oncol       Date:  2014-04-23       Impact factor: 5.344

4.  Early complications of high-dose-rate brachytherapy in soft tissue sarcoma: a comparison with traditional external-beam radiotherapy.

Authors:  Cynthia L Emory; Corey O Montgomery; Benjamin K Potter; Martin E Keisch; Sheila A Conway
Journal:  Clin Orthop Relat Res       Date:  2012-03       Impact factor: 4.176

5.  Unplanned excision of soft tissue sarcoma results in increased rates of local recurrence despite full further oncological treatment.

Authors:  Y A Qureshi; J R Huddy; J D Miller; D C Strauss; J M Thomas; A J Hayes
Journal:  Ann Surg Oncol       Date:  2011-07-27       Impact factor: 5.344

6.  The impact of residual disease on local recurrence in patients treated by initial unplanned resection for soft tissue sarcoma of the extremity.

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Journal:  J Surg Oncol       Date:  1997-10       Impact factor: 3.454

7.  Risk factors for local recurrence and metastasis in soft tissue sarcomas of the extremity.

Authors:  Aaron Sabolch; Mary Feng; Kent Griffith; Callie Rzasa; Laura Gadzala; Felix Feng; Janet Sybil Biermann; Rashmi Chugh; Michael Ray; Edgar Ben-Josef
Journal:  Am J Clin Oncol       Date:  2012-04       Impact factor: 2.339

8.  A system for the surgical staging of musculoskeletal sarcoma.

Authors:  W F Enneking; S S Spanier; M A Goodman
Journal:  Clin Orthop Relat Res       Date:  1980 Nov-Dec       Impact factor: 4.176

9.  Soft tissue sarcoma should be treated at a tumor center. A comparison of quality of surgery in 375 patients.

Authors:  P Gustafson; K E Dreinhöfer; A Rydholm
Journal:  Acta Orthop Scand       Date:  1994-02

10.  The effect of an unplanned excision of a soft-tissue sarcoma on prognosis.

Authors:  C R Chandrasekar; H Wafa; R J Grimer; S R Carter; R M Tillman; A Abudu
Journal:  J Bone Joint Surg Br       Date:  2008-02
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  4 in total

1.  High-grade myxofibrosarcoma of the abdominal wall.

Authors:  Richard Antbring; Sam G Parker; Jeffrey T Lordan; Alastair Cj Windsor
Journal:  BMJ Case Rep       Date:  2017-06-02

2.  Assessing the Safety and Utility of Wound VAC Temporization of the Sarcoma or Benign Aggressive Tumor Bed Until Final Margins Are Achieved.

Authors:  Mitchell S Fourman; Duncan C Ramsey; Erik T Newman; Joseph H Schwab; Yen-Lin Chen; Yin P Hung; Ivan Chebib; Vikram Deshpande; G Petur Nielsen; Thomas F DeLaney; John T Mullen; Kevin A Raskin; Santiago A Lozano Calderón
Journal:  Ann Surg Oncol       Date:  2021-11-09       Impact factor: 5.344

3.  Upper extremity sarcoma: impact of current practice guidelines and controversies on reconstructive approaches.

Authors:  Marek Dobke; Gina A Mackert
Journal:  SICOT J       Date:  2017-02-21

4.  Temporizing Wound VAC Dressing Until Final Negative Margins are Achieved Reduces Myxofibrosarcoma Local Recurrence.

Authors:  Mitchell S Fourman; Duncan C Ramsey; Justin Kleiner; Anser Daud; Erik T Newman; Joseph H Schwab; Yen-Lin Chen; Thomas F DeLaney; John T Mullen; Kevin A Raskin; Santiago A Lozano-Calderón
Journal:  Ann Surg Oncol       Date:  2021-06-18       Impact factor: 5.344

  4 in total

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