Mehmet Özgür Avinçsal1, Yurie Hiroshima2, Hitomi Shinomiya2, Hirotaka Shinomiya2, Naoki Otsuki3, Ken-Ichi Nibu2. 1. Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, Japan; Department of Otorhinolaryngology, Gaziosmanpasa Taksim Training and Research Hospital, Turkey. 2. Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, Japan. 3. Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, Japan. Electronic address: naokies@med.kobe-u.ac.jp.
Abstract
OBJECTIVE: First bite syndrome is the development of pain in the ipsilateral parotid region after the first few bites of food and can be seen after surgery of the upper cervical region. The aim of this study is to highlight the etiology of this potentially debilitating chronic pain syndrome. MATERIALS AND METHODS: Retrospective review of 53 patients undergoing surgery of the upper neck between 2002 and 2013. RESULTS: FBS developed in 16 patients (30%). Partial resolution of FBS symptoms occurred in 69% and complete resolution in 12%, whereas 15% had no change. FBS was most common in the patients who had tumor arising from deep lobe of parotid gland in comparison with other sites (50% vs 18%, p=0.017). FBS developed in 57% of patients undergoing external carotid artery (ECA) ligation and in 12.5% of patients in whom ECA was preserved (p=0.0008). Among the patients in whom ECA was preserved, FBS developed in 43% of the patients in whom sympathetic chain was sacrificed and in 4% of the patients in whom sympathetic chain was preserved. CONCLUSION: Present results further support the role of sympathetic chain in the development of FBS.
OBJECTIVE: First bite syndrome is the development of pain in the ipsilateral parotid region after the first few bites of food and can be seen after surgery of the upper cervical region. The aim of this study is to highlight the etiology of this potentially debilitating chronic pain syndrome. MATERIALS AND METHODS: Retrospective review of 53 patients undergoing surgery of the upper neck between 2002 and 2013. RESULTS:FBS developed in 16 patients (30%). Partial resolution of FBS symptoms occurred in 69% and complete resolution in 12%, whereas 15% had no change. FBS was most common in the patients who had tumor arising from deep lobe of parotid gland in comparison with other sites (50% vs 18%, p=0.017). FBS developed in 57% of patients undergoing external carotid artery (ECA) ligation and in 12.5% of patients in whom ECA was preserved (p=0.0008). Among the patients in whom ECA was preserved, FBS developed in 43% of the patients in whom sympathetic chain was sacrificed and in 4% of the patients in whom sympathetic chain was preserved. CONCLUSION: Present results further support the role of sympathetic chain in the development of FBS.
Authors: Aldo Eguiluz-Melendez; Sergio Torres-Bayona; María Belen Vega; Vanessa Hernández-Hernández; Erik W Wang; Carl H Snyderman; Paul A Gardner Journal: J Neurol Surg B Skull Base Date: 2021-02-22