Literature DB >> 27526197

Epidemiology and mechanisms of gastroesophageal reflux disease in the elderly: a perspective.

Mohammad Bashashati1, Irene Sarosiek1, Richard W McCallum2.   

Abstract

Gastroesophageal reflux disease (GERD) seems to be more common in older individuals. Disturbed esophageal motility; anatomical disorders, such as hiatal hernia, increased obesity, defective mucosal integrity, and alteration in salivary secretion; and concomitant medications all attribute to the higher rate of GERD in the elderly. In this review, we discuss the underlying mechanisms that could explain this higher rate of GERD in the elderly.
© 2016 New York Academy of Sciences.

Entities:  

Keywords:  elderly; epidemiology; gastroesophageal reflux disease; pathophysiology; severity

Mesh：

Year:  2016        PMID： 27526197     DOI： 10.1111/nyas.13196

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  6 in total

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Journal:  Med Pharm Rep       Date:  2019-10-25

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Authors:  Yu Ding; Huiru Hou; Miao Liu; Xiaoyuan Wang; Yue Xu; Haiyan Shi; Haitao Du; Liyuan Wang
Journal:  Biomed Res Int       Date:  2021-01-25       Impact factor: 3.411

Review 4.  Management of gastroesophageal reflux disease in adults: a pharmacist's perspective.

Authors:  Brett MacFarlane
Journal:  Integr Pharm Res Pract       Date:  2018-06-05

5.  It Is Time to Meet the Challenges of the Changing Epidemiology of Gastroesophageal Reflux Disease.

Authors:  Gwang Ha Kim
Journal:  J Neurogastroenterol Motil       Date:  2018-10-01       Impact factor: 4.924

6.  Gastroesophageal reflux disease in a typical African population: a symptom-based multicenter study.

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  6 in total

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